Characterization of a flexible cap for simultaneous OPM-MEG and EEG measurements
Autor(in); Institution
Anders, Paul; 8.2, Biosignale, PTB-Berlin
Brickwedde, Marion; 8.2, Biosignale, PTB-Berlin; Department of Child and Adolescent Psychiatry, Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, GERMANY
Grent-’t-Jong, T.; Department of Child and Adolescent Psychiatry, Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, GERMANY; Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, UNITED KINGDOM
Krüger, Peter; 8.2, Biosignale, PTB-Berlin
Haueisen, J.; Institute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, GERMANY
Uhlhaas, P.-J.; Department of Child and Adolescent Psychiatry, Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, GERMANY; Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, UNITED KINGDOM
OPM ; MEG ; EEG ; multimodal ; flexible cap ; characterization ; 3D scanning
Zusammenfassung
Objective.Combining magnetoencephalography (MEG) and electroencephalography (EEG) can lead to more accurate source reconstruction results. Previous efforts of simultaneous EEG and MEG using optically pumped magnetometers (OPM-MEG) used a two-layer setup, where a helmet or cap with mounted OPMs was worn on top of an EEG cap, resulting in decreased OPM signal amplitudes. This is inevitable for rigid OPM-MEG helmets used by most research groups, which are often heavy and need fixation, require time-consuming customization or do not adapt to different head shapes, diminishing the advantages of OPM-MEG. In this study, we therefore aimed to create a flexible cap that enables fully integrated simultaneous OPM-MEG and EEG measurements, which are suitable for source reconstruction and yield the same signal quality as each individual modality.
Approach.We integrated OPM mounts into a commercial EEG cap and implemented a sensor localization pipeline based on co-registering the known OPM mount geometry to 3D scans of participants wearing the cap. In a multi-paradigm experiment with five volunteers, we investigated how much OPMs shift during an experiment due to head movements of the participant. We also compared signal-to-noise ratios and artifact strengths between single-modality and multimodal measurements.
Main results.The distribution of changes in OPM positions and orientations are within acceptable limits for source reconstruction as published in a simulation study. Occipital OPMs experienced larger shifts. No systematic difference in signal-to-noise ratios or artifact strengths between single-modality and multimodal acquisition could be observed, indicating no signal degradation due to the presence of the other modality.
Significance.Measuring simultaneous OPM-MEG and EEG using a flexible cap could improve source reconstruction results and help to bring OPM-MEG to clinical settings due to easier comparison and verification with the established EEG, which is relevant for presurgical epilepsy evaluation.
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Open Access Hybrid
Rechteinformation
CC BY 4.0 ; Creative Commons Attribution 4.0 License
Themenbereich der Metrologie
Metrologie in der Medizin
Förderinformationen (1)
Förderername: Deutsche Forschungsgemeinschaft
Förderer ID: 0000 0001 2096 9829
Förderer ID Typ: ISNI
Förderungsnummer: Project-ID 460785001
Förderinformationen (2)
Förderername: Medical Research Council (MRC)
Förderer ID: 0000 0001 2247 8951
Förderer ID Typ: ISNI
Förderungsnummer: MR/L011689/1
Zitierung
Anders, P., Brickwedde, M., Grent-’t-Jong, T., Krüger, P., Haueisen, J., Uhlhaas, P.-J., & Sander-Thömmes, T. (2026). Characterization of a flexible cap for simultaneous OPM-MEG and EEG measurements. Journal of Neural Engineering, 23(3), 1–12. https://doi.org/10.1088/1741-2552/ae60cf
