Zugriffsnummer 54555
Dokumenttyp Zeitschriftenartikel Open Access Hybrid
Peer Review mit Peer Review
Sprache Englisch
Titel Artifacts in cardiac T1 and T2 mapping techniques – Influence on reliable quantification
Autor(in); Institution
Fenski, Maximilian; Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, GERMANY; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK
Gröschel, Jan; Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, GERMANY
Gatehouse, Peter; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK
Kolbitsch, Christoph; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Schulz-Menger, Jeanette; Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Experimental and Clinical Research Center, Berlin, GERMANY
Quelle/Jahr Journal of Cardiovascular Magnetic Resonance: 27 (2025), 2, 1 - 16
Artikelnummer 101934
ISSN 1097-6647 (print) ; 1532-429X (online)
DOI
Verlag [Amsterdam]: Elsevier
Freie Schlagworte Cardiovascular magnetic resonance ; T1 mapping ; T2 mapping ; Magnetic resonance imaging artifacts ; Image quality assurance
Zusammenfassung Cardiac T1 and T2 mapping techniques are well-established methods for obtaining quantitative pixelwise representations of myocardial tissue properties. Mapping images are commonly evaluated quantitatively, and their resulting values play a crucial role in diagnosis and therapeutic decision making in various cardiac pathologies. Despite the validated effectiveness of these techniques, both methodological and patient-specific confounders must be considered when applying them in clinical and research settings. Artifacts - erroneous features within the MR image - can be misinterpreted as true anatomical structures or pathologies, potentially confounding quantitative analyses, conducted by both human readers and AI algorithms. Artifacts can arise from sources such as patient motion, metal objects, hardware constraints, patient-specific scanner adjustments (e.g. flip-angle calibration) and processing errors, particularly within the complex environment of cardiac imaging. While artifact sources in other CMR sequences are well documented, cardiac parametric mapping presents unique challenges due to its distinct image generation and quantitative assessment. This article provides an overview of artifacts encountered in cardiac T1 and T2 mapping, along with a concise explanation of their origins, aiming to raise awareness of their potential impact on clinical decision making. Future developments, including sequences designed to mitigate mapping artifacts, are also briefly discussed. A strong interaction between scientists and clinicians is needed to overcome these challenges and maintain the reliability of quantification results.
Kostenfreier Zugang Open Access Hybrid
Rechteinformation CC BY 4.0 ; Creative Commons Attribution 4.0 License
Förderinformationen (1) Förderername: German Heart Foundation

Zitierung

Fenski, M., Gröschel, J., Gatehouse, P., Kolbitsch, C., & Schulz-Menger, J. (2025). Artifacts in cardiac T1 and T2 mapping techniques – Influence on reliable quantification. Journal of Cardiovascular Magnetic Resonance, 27(2), 1–16. https://doi.org/10.1016/j.jocmr.2025.101934

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