T2 mapping of the prostate at 7 Tesla: A feasibility study
Autor(in); Institution
Bonanno, Gabriele; Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Bern, SWITZERLAND; Magnetic Resonance Methodology, Institute of Diagnostic and Interventional Neuroradiology, University of Bern, Bern, SWITZERLAND; Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland, Bern, SWITZERLAND
Jung, Bernd; Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland, Bern, SWITZERLAND; Dept. of Diagnostic, Interventional and Pediatric Radiology, Inselspital, Bern University Hospital, SWITZERLAND, Bern, SWITZERLAND
Kreis, Roland; Magnetic Resonance Methodology, Institute of Diagnostic and Interventional Neuroradiology, University of Bern, Bern, SWITZERLAND; Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland, Bern, SWITZERLAND
Schmitter, Sebastian; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin; Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, GERMANY, Heidelberg, Germany; Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, USA
Obmann, Verena C; Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland, Bern, SWITZERLAND; Dept. of Diagnostic, Interventional and Pediatric Radiology, Inselspital, Bern University Hospital, Switzerland, Bern, SWITZERLAND
Kober, Tobias; Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland, Lausanne, SWITZERLAND; Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, Lausanne, SWITZERLAND; LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, Lausanne, SWITZERLAND
Hilbert, Tom; Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland, Lausanne, SWITZERLAND; Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, Lausanne, SWITZERLAND; LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, Lausanne, SWITZERLAND
Quelle/Jahr
Proceedings of the International Society for Magnetic Resonance in Medicine:(2024), 1
- 2
Quantitative MRI biomarkers such as the apparent di"usion coe!cient have shown to be a valuable tool to detect prostate cancer. Similarly, T2 relaxometry has shown potential to distinguish between prostate cancer and healthy tissue at 3T. At ultrahigh field (UHF), T2 mapping has been little explored, mainly in advance centers, potentially due to limited B1 homogeneity and effiency at the location of the prostate. However, UHF imaging becomes more accessible for clinical exams because the use of parallel transmission (pTx) has become more streamlined and especially more robust while abdominal/pelvic RF coils more available.
We investigated the use of multi-echo spin echo (MESE) and fast T -prepared 3D FLASH sequences in combination with an
established static pTx (RF shimming) procedure for T2 mapping in the prostate. MESE is robust but requires long acquisition times (TA) and is limited to 2D imaging due to high SAR for the application of multiple refocusing pulses. Alternatively, T2 -prepared (T2 p) approaches combined with fast gradient echo sequences are more SAR efficient and allow for larger volumetric coverage. Here we report preliminary in vivo tests in our research setting.
Zitierung
Bonanno, G., Jung, B., Kreis, R., Schmitter, S., Obmann, V. C., Kober, T., & Hilbert, T. (2024). T₂ mapping of the prostate at 7 Tesla: A feasibility study. ISMRM & ISMRT Annual Meeting & Exhibition, Singapore, 04-09, Mai, 2024, Singapore. https://doi.org/10.58530/2024/0525
