Zugriffsnummer 51605
Dokumenttyp Zeitschriftenartikel Open Access Gold
Peer Review mit Peer Review
Sprache Englisch
Titel Benchmarking the influence of pre-training on explanation performance in MR image classification
Autor(in); Institution
Oliveira, Marta; 8.4, Mathematische Modellierung und Datenanalyse, PTB-Berlin
Wilming, Rick; Computer Science Department, Technische Universität Berlin, Berlin, GERMANY
Clark, Benedict; 8.4, Mathematische Modellierung und Datenanalyse, PTB-Berlin
Budding, Céline; Berlin Center for Advanced Neuroimaging (BCAN), Charité -Universitätsmedizin Berlin, Berlin, GERMANY
Eitel, Fabian; Berlin Center for Advanced Neuroimaging (BCAN), Charité -Universitätsmedizin Berlin, Berlin, GERMANY
Ritter, Kerstin; Berlin Center for Advanced Neuroimaging (BCAN), Charité -Universitätsmedizin Berlin, Berlin, GERMANY
Haufe, Stefan; 8.4, Mathematische Modellierung und Datenanalyse, PTB-Berlin; Computer Science Department, Technische Universität Berlin, Berlin, GERMANY; Berlin Center for Advanced Neuroimaging (BCAN), Charité -Universitätsmedizin Berlin, Berlin, GERMANY
Quelle/Jahr Frontiers in Artificial Intelligence: 7 (2024), 01 - 10
Artikelnummer 1330919
Availability [online only]
ISSN 2624-8212 (online)
DOI
Verlag Lausanne: Frontiers
Freie Schlagworte XAI ; explainability ; interpretability ; pre-training ; MRI ; benchmark ; dataset ; classification
Zusammenfassung Convolutional Neural Networks (CNNs) are frequently and successfully used in medical prediction tasks. They are often used in combination with transfer learning, leading to improved performance when training data for the task are scarce. The resulting models are highly complex and typically do not provide any insight into their predictive mechanisms, motivating the field of “explainable” artificial intelligence (XAI). However, previous studies have rarely quantitatively evaluated the “explanation performance” of XAI methods against ground-truth data, and transfer learning and its influence on objective measures of explanation performance has not been investigated. Here, we propose a benchmark dataset that allows for quantifying explanation performance in a realistic magnetic resonance imaging (MRI) classification task. We employ this benchmark to understand the influence of transfer learning on the quality of explanations. Experimental results show that popular XAI methods applied to the same underlying model differ vastly in performance, even when considering only correctly classified examples. We further observe that explanation performance strongly depends on the task used for pre-training and the number of CNN layers pre-trained. These results hold after correcting for a substantial correlation between explanation and classification performance.
Kostenfreier Zugang Open Access Gold
Rechteinformation CC BY 4.0 ; Creative Commons Attribution 4.0 License
Themenbereich der Metrologie Metrologie in der Medizin
Forschungsprojekt (internes Projekt: Heidenhain)
Förderinformationen (1) Förderername: Heidenhain Institution
Förderprogramm: Nachwuchsforschergruppe im Bereich Maschinelles Lernen
Förderungsnummer: 1W-84027

Zitierung

Oliveira, M., Wilming, R., Clark, B., Budding, C., Eitel, F., Ritter, K., & Haufe, S. (2024). Benchmarking the influence of pre-training on explanation performance in MR image classification. Frontiers in Artificial Intelligence, 7, 01–10. https://doi.org/10.3389/frai.2024.1330919

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