| Zugriffsnummer | 51407 |
| Dokumenttyp | Zeitschriftenartikel |
| Peer Review | mit Peer Review |
| Sprache | Englisch |
| Titel | Charge collection efficiency of commercially available parallel-plate ionisation chambers in ultra-high dose-per-pulse electron beams |
| Autor(in); Institution |
Bourgouin, Alexandra; PTB-Braunschweig, formerly
Paz-Martin, Jose; Departamento de Física de Partículas, Universidad de Santiago, Santiago de Compostela, SPAIN
Gedik, Yunus Can; PTB-Braunschweig, formerly
Frei, Franziska; Eidgenössisches Institut für Metrologie (METAS), Bern-Wabern, SWITZERLAND
Peier, Peter; Eidgenössisches Institut für Metrologie (METAS), Bern-Wabern, SWITZERLAND
Rossomme, Séverine; IBA, Louvain-la-Neuve, BELGIUM
Schönfeld, Andreas; Sun Nuclear, A Mirion Medical Company, Melbourne, FL, USA
Schüller, Andreas; 6.2, Dosimetrie für Strahlentherapie und Röntgendiagnostik, PTB-Braunschweig
Gomez Rodriguez, Faustino; Departamento de Física de Partículas, Universidad de Santiago, Santiago de Compostela, SPAIN
Kapsch, Ralf-Peter; 6.2, Dosimetrie für Strahlentherapie und Röntgendiagnostik, PTB-Braunschweig
|
| Quelle/Jahr | Physics in Medicine and Biology: 68 (2023), 23, 1 - 15 |
| Artikelnummer | 235002 |
| ISSN | 0031-9155 (print) ; 1361-6560 (online) |
| DOI | |
| Verlag | Bristol: IOP Publishing |
| Freie Schlagworte | Ionization chamber ; Saturation effect ; Ultra-high dose per pulse ; Electron beam ; FLASH dosimetry |
| Zusammenfassung | Objective. This investigation aims to experimentally determine the charge collection efficiency (CCE) of six commercially available parallel-plate ionisation chamber (PPIC) models in ultra-high dose-per-pulse (UHDPP) electron beams. Approach. The CCE of 22 PPICs has been measured in UHDPP electron beams at the National Metrology Institution of Germany (PTB). The CCE was determined for a dose per pulse (DPP) range between 0.1 and 6.4 Gy (pulse duration of 2.5 μs). The results obtained with the different PPICs were compared to evaluate the reproducibility, intra- and inter-model variation, and the performance of a CCE empirical model. Main results. The intra-model variation was, on average, 4.0%, which is more than three times the total combined relative standard uncertainty and was found to be greater at higher DPP (up to 20%). The inter-model variation for the PPIC with 2 mm electrode spacing, which was found to be, on average, 10%, was also significant compared to the relative uncertainty and the intra-model variation. The observed CCE variation could not be explained only by the expected deviation of the electrode spacing from the nominal value within the manufacturing tolerance. It should also be noted that a substantial polarity effect, between 0.914(5) and 1.201(3), was observed, and significant intra- and inter-model variation was observed on this effect. Significance. For research and pre-clinical study, the commercially available PPIC with a well-known CCE (directly measured for the specific chamber) and with a small electrode spacing could be used for relative and absolute dosimetry with a lower-limit uncertainty of 1.6% (k = 1) in the best case. However, to use a PPIC as a secondary standard in UHDPP electron beams for clinical purposes would require new model development to reduce the ion recombination, the polarity effect, and the total standard uncertainty on the dose measurement. |
| Kostenfreier Zugang | Open Access Hybrid |
| Rechteinformation | CC BY 4.0 ; Creative Commons Attribution 4.0 License |
| Förderinformationen (1) |
Förderername: European Commission (EC)
Förderer ID: 0000 0001 2242 8989 Förderer ID Typ: ISNI Förderprogramm: EMPIR 2018 Health Titel der Förderung: 18HLT04: UHDpulse: Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates Förderungsnummer: 18HLT04 |
Zitierung
Bourgouin, A., Paz-Martin, J., Gedik, Y. C., Frei, F., Peier, P., Rossomme, S., Schönfeld, A., Schüller, A., Gomez Rodriguez, F., & Kapsch, R.-P. (2023). Charge collection efficiency of commercially available parallel-plate ionisation chambers in ultra-high dose-per-pulse electron beams. Physics in Medicine and Biology, 68(23), 1–15. https://doi.org/10.1088/1361-6560/ad0a58