| Zugriffsnummer | 50875 |
| Dokumenttyp | Zeitschriftenartikel |
| Peer Review | mit Peer Review |
| Sprache | Englisch |
| Titel | Temperature dependent magnetorelaxometry of magnetic nanoparticle ensembles |
| Autor(in); Institution |
Eberbeck, Dietmar; 8.2, Biosignale, PTB-Berlin
Jaufenthaler, A.; Institute of Electrical and Biomedical Engineering, UMIT TIROL-Private University for Health Sciences and Health Technology, Hall in Tirol, AUSTRIA
Baumgarten, D.; Institute of Electrical and Biomedical Engineering, UMIT TIROL-Private University for Health Sciences and Health Technology, Hall in Tirol, AUSTRIA
|
| Quelle/Jahr | Physics in Medicine and Biology: 68 (2023), 17, 1 - 9 |
| Artikelnummer | 175017 |
| ISSN | 0031-9155 (print) ; 1361-6560 (online) |
| DOI | |
| Verlag | Bristol: IOP |
| Freie Schlagworte | magnetic nanoparticles ; relaxation signal ; temperature ; magnetorelaxometry |
| Zusammenfassung | Magnetorelaxometry imaging (MRXI) is a non-invasive, quantitative imaging technique for magnetic nanoparticles (MNPs). The image resolution of this technique significantly depends on the relaxation amplitude (ΔB). For this work, we measured the room emperature (299 K) relaxation signals of eight commercial MNP sample systems with different magnetic properties, in both fluid and immobilized states, in order to select the most suitable sample for a particular MRXI setting. Additionally, the effect of elevated temperatures (up to hyperthermia temperature, 335K) on the relaxation signals of four different MNP systems (Synomag, Perimag, BNF and Nanomag) in both states were investigated. The ΔB values of fluid samples significantly decreased with increasing temperature, and the behaviour for immobilized samples depended on their blocking temperature (TB). For samples with TB<299 K, ΔB also decreased with increasing temperature. Whereas for samples with TB>299 K, the opposite behaviour was observed. These results are beneficial for improving the image resolution in MRXI and show, among the investigated systems, and for our setup, Synomag is the best candidate for future in vitro and in vivo studies. This is due to its consistently high ΔB between 299 and 335Kin both states. Our findings demonstrate the feasibility of temperature imaging by MRXI. |
| Kostenfreier Zugang | Open Access Hybrid |
| Rechteinformation | CC BY 4.0 ; Creative Commons Attribution 4.0 License |
| Themenbereich der Metrologie | Metrologie in der Medizin |
Zitierung
Arsalani, S., Radon, P., Eberbeck, D., Körber, R., Jaufenthaler, A., Baumgarten, D., & Wiekhorst, F. (2023). Temperature dependent magnetorelaxometry of magnetic nanoparticle ensembles. Physics in Medicine and Biology, 68(17), 1–9. https://doi.org/10.1088/1361-6560/acec28