| Zugriffsnummer | 50354 |
| Dokumenttyp | Zeitschriftenartikel |
| Peer Review | mit Peer Review |
| Sprache | Englisch |
| Titel | Wirelessly interfacing sensor-equipped implants and MR scanners for improved safety and imaging |
| Autor(in); Institution | |
| Quelle/Jahr | Magnetic Resonance in Medicine: 90 (2023), 6, 2608 - 2626 |
| ISSN | 0740-3194 (print) ; 1522-2594 (online) |
| DOI | |
| Verlag | New York, NY: Wiley / ISMRM |
| Freie Schlagworte | active implantable medical devices ; Bluetooth low energy ; deep brain stimulation ; MR safety ; neural implants ; RF heating |
| Zusammenfassung | Purpose: To investigate a novel reduced RF heating method for imaging in the presence of active implanted medical devices (AIMDs) which employs a sensor-equipped implant that provides wireless feedback. Methods: The implant, consisting of a generator case and a lead, measures RF-induced E-fields at the implant tip using a simple sensor in the generator case and transmits these values wirelessly to the MR scanner. Based on the sensor signal alone, parallel transmission (pTx) excitation vectors were calculated to suppress tip heating and maintain image quality. A sensor-based imaging metric was introduced to assess the image quality. The methodology was studied at 7T in testbed experiments, and at a 3T scanner in an ASTM phantom containing AIMDs instrumented with six realistic deep brain stimulation (DBS) lead configurations adapted from patients. Results: The implant successfully measured RF-induced E-fields (Pearson correlation coefficient squared [R2] = 0.93) and temperature rises (R2 = 0.95) at the implant tip. The implant acquired the relevant data needed to calculate the pTx excitation vectors and transmitted them wirelessly to the MR scanner within a single shot RF sequence (<60 ms). Temperature rises for six realistic DBS lead configurations were reduced to 0.03–0.14 K for heating suppression modes compared to 0.52–3.33 K for the worst-case heating, while imaging quality remained comparable (five of six lead imaging scores were ≥0.80/1.00) to conventional circular polarization (CP) images. Conclusion: Implants with sensors that can communicate with an MR scanner can substantially improve safety for patients in a fast and automated manner, easing the current burden for MR personnel. |
| Kostenfreier Zugang | Open Access Hybrid |
| Rechteinformation | CC BY 4.0 ; Creative Commons Attribution 4.0 License |
| Themenbereich der Metrologie | Metrologie in der Medizin |
| Forschungsprojekt | 21NRM05: STASIS: Standardisation for safe implant scanning in MRI |
| Förderinformationen (1) |
Förderername: European Commission (EC)
Förderer ID: 0000 0001 2242 8989 Förderer ID Typ: ISNI Förderprogramm: Metrology Partnership 2021 Normative Titel der Förderung: 21NRM05: STASIS: Standardisation for safe implant scanning in MRI Förderungsnummer: 21NRM05 |