| Zugriffsnummer | 48883 |
| Dokumenttyp | Zeitschriftenartikel |
| Peer Review | mit Peer Review |
| Sprache | Englisch |
| Titel | Absorbed-dose-to-water measurement using alanine in ultra-high-pulse-dose-rate electron beams |
| Autor(in); Institution |
Hackel, Thomas; 6.2, Dosimetrie für Strahlentherapie und Röntgendiagnostik, PTB-Braunschweig
Marinelli, Marco; University of Rome Tor Vergata, Industrial Engineering Dept., Rome, ITALY
Kranzer, Rafael; PTW Dosimetry, Germany University Clinic for Medical Radiation Physics, Medical Campus Pius Hospital, Carl von Ossietzky University Oldenburg, GERMANY
Kapsch, Ralf-Peter; 6.2, Dosimetrie für Strahlentherapie und Röntgendiagnostik, PTB-Braunschweig
|
| Quelle/Jahr | Physics in Medicine and Biology: 67 (2022), 20, 1 - 11 |
| Artikelnummer | 205011 |
| ISSN | 0031-9155 (PRINT) ; 1361-6560 (ONLINE) |
| DOI | |
| Verlag | Bristol: IOP Publishing |
| Freie Schlagworte | Alanine dosimetry ; UHDPR ; Monte Carlo ; Electron beam ; Integrating current transformer (ICT) |
| Zusammenfassung | Objective: The aim of the presented study is to evaluate the dose response of the PTB’s secondary standard system, which is based on alanine and electron spin resonance (ESR) spectroscopy measurement, in ultra-high-pulse-dose-rate (UHPDR) electron beams. Approach: The alanine dosimeter system was evaluated in the PTB’s UHPDR electron beams (20 MeV) in a range of 0.15 Gy to 6.2 Gy per pulse. The relationship between the obtained absorbed dose to water per pulse and the in-beamline charge measurement of the electron pulses acquired using an integrating current transformer (ICT) was evaluated. Monte Carlo simulations were used to determine the beam quality conversion and correction factors required to perform alanine dosimetry. Main results: The beam quality conversion factor from the reference quality 60Co to 20 MeV obtained by Monte Carlo simulation, 1.010(1), was found to be within the standard uncertainty of the consensus value, 1.014(5). The dose-to-water relative standard uncertainty was determined to be 0.68 % in PTB’s UHPDR electron beams. Significance: In this investigation, the dose-response of the PTB’s alanine dosimeter system was evaluated in a range of dose per pulse between 0.15 Gy and 6.2 Gy and no evidence of dose-response dependency of the PTB’s secondary standard system based on alanine was observed. The alanine/ESR system was shown to be a precise dosimetry system for evaluating absorbed dose to water in UHPDR electron beams. |
| Kostenfreier Zugang | Open Access Hybrid |
| Rechteinformation | CC BY 4.0 ; Creative Commons Attribution 4.0 License |
| Forschungsprojekt | 18HLT04: UHDpulse: Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates |
| Förderinformationen (1) |
Förderername: European Commission (EC)
Förderer ID: 0000 0001 2242 8989 Förderer ID Typ: ISNI Förderprogramm: EMPIR 2018 Health Titel der Förderung: 18HLT04: UHDpulse: Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates Förderungsnummer: 18HLT04 |
Zitierung
Bourgouin, A., Hackel, T., Marinelli, M., Kranzer, R., Schüller, A., & Kapsch, R.-P. (2022). Absorbed-dose-to-water measurement using alanine in ultra-high-pulse-dose-rate electron beams. Physics in Medicine and Biology, 67(20), 1–11. https://doi.org/10.1088/1361-6560/ac950b