Schulz‐Menge, J.; Experimental and Clinical Research Center, A Joint Cooperation between the Charité Medical Faculty and the Max-Delbrueck Center for Molecular Medicine and HELIOS Hospital Berlin Buch, Berlin, GERMANY; DZHK (German Center for Cardiovascular Research), Partner Site Berlin, Berlin, GERMANY; Helios Clinics Berlin-Buch Department of Cardiology and Nephrology, Berlin, GERMANY
Schäffter, Tobias; 8, Medizinphysik und metrologische Informationstechnik, PTB-Berlin; Department of Medical Engineering, Technische Universität Berlin, GERMANY
Schmitter, Sebastian; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin; Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA
Quelle/Jahr
Magnetic Resonance in Medicine: 87
(2022), 6, 2621
- 2636
Purpose: Respiratory motion-compensated (MC) 3D cardiac fat-water imaging at 7T.
Methods: Free-breathing bipolar 3D triple-echo gradient-recalled-echo (GRE) data with radial phase-encoding (RPE) trajectory were acquired in 11 healthy volunteers (7M\\4F, 21–35 years, mean: 30 years) with a wide range of body mass index (BMI; 19.9–34.0 kg/m2) and volunteer tailored B1+ shimming. The bipolar-corrected triple-echo GRE-RPE data were binned into different respiratory phases (self-navigation) and were used for the estimation of non-rigid motion vector fields (MF) and respiratory resolved (RR) maps of the main magnetic field deviations (ΔB0). RR ΔB0 maps and MC ΔB0 maps were compared to a reference respiratory phase to assess respiration-induced changes. Subsequently, cardiac binned fat-water images were obtained using a model-based, respiratory motion-corrected image reconstruction.
Results: The 3D cardiac fat-water imaging at 7T was successfully demonstrated. Local respiration-induced frequency shifts in MC ΔB0 maps are small compared to the chemical shifts used in the multi-peak model. Compared to the reference exhale ΔB0 map these changes are in the order of 10 Hz on average. Cardiac binned MC fat-water reconstruction reduced respiration induced blurring in the fat-water images, and flow artifacts are reduced in the end-diastolic fat-water separated images.
Conclusion: This work demonstrates the feasibility of 3D fat-water imaging at UHF for the entire human heart despite spatial and temporal B1+ and B0 variations, as well as respiratory and cardiac motion.
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Open Access Hybrid
Rechteinformation
CC BY 4.0 ; Creative Commons Attribution 4.0 License
Themenbereich der Metrologie
Metrologie in der Medizin
Zitierung
Dietrich, S., Aigner, C. S., Mayer, J., Kolbitsch, C., Schulz‐Menge, J., Schäffter, T., & Schmitter, S. (2022). Motion‐compensated fat‐water imaging for 3D cardiac MRI at ultra‐high fields. Magnetic Resonance in Medicine, 87(6), 2621–2636. https://doi.org/10.1002/mrm.29144
