Zugriffsnummer 47779
Dokumenttyp Buchartikel Freier Zugang
Peer Review mit Peer Review
Sprache Englisch
Titel Quantitative assessment of renal perfusion and oxygenation by invasive probes: basic concepts
Autor(in); Institution
Cantow, K.; Institut für vegetative Physiologie, Charité, Universitätsmedizin Berlin, Berlin, GERMANY
Evans, R.G.; Cardiovascular Disease Program, Biosciences Discovery Institute and Department of Physiology, Monash University, Melbourne, AUSTRALIA
Grosenick, Dirk; 8.3, Biomedizinische Optik, PTB-Berlin
Gladytz, T.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, GERMANY
Niendorf, T.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, GERMANY
Flemming, B.; Institut für vegetative Physiologie, Charité, Universitätsmedizin Berlin, Berlin, GERMANY
Seeliger, E.; Institut für vegetative Physiologie, Charité, Universitätsmedizin Berlin, Berlin, GERMANY
Quelle/Jahr Preclinical MRI of the Kidney: Methods and Protocols:(2021), 89 - 107
Schriftenreihe Methods in Molecular Biology (MIMB): 2216
Herausgeber(in)
Pohlmann, Andreas
Niendorf, Thoralf
ISBN 978-1-0716-0977-4 (PRINT) ; 978-1-0716-0978-1 (ONLINE)
DOI
Verlag New York, NY: Springer
Freie Schlagworte Renal hemodynamics and oxygenation ; In vivo methods ; In vivo methods
Zusammenfassung Renal tissue hypoperfusion and hypoxia are early key elements in the pathophysiology of acute kidney injury of various origins, and may also promote progression from acute injury to chronic kidney disease. Here we describe basic principles of methodology to quantify renal hemodynamics and tissue oxygenation by means of invasive probes in experimental animals. Advantages and disadvantages of the various methods are discussed in the context of the heterogeneity of renal tissue perfusion and oxygenation. This chapter is based upon work from the COST Action PARENCHIMA, a community-driven network funded by the European Cooperation in Science and Technology (COST) program of the European Union, which aims to improve the reproducibility and standardization of renal MRI biomarkers. This introduction chapter is complemented by a separate chapter describing the experimental procedure and data analysis.
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Rechteinformation CC BY 4.0 ; Creative Commons Attribution 4.0 License
Themenbereich der Metrologie Metrologie in der Medizin

Zitierung

Cantow, K., Evans, R., Grosenick, D., Gladytz, T., Niendorf, T., Flemming, B., & Seeliger, E. (2021). Quantitative assessment of renal perfusion and oxygenation by invasive probes: basic concepts. In A. Pohlmann & T. Niendorf (Eds.), Preclinical MRI of the Kidney: Methods and Protocols (pp. 89–107). New York, NY: Springer. https://doi.org/10.1007/978-1-0716-0978-1_6

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