| Zugriffsnummer | 45335 |
| Dokumenttyp | Zeitschriftenartikel |
| Peer Review | mit Peer Review |
| Sprache | Englisch |
| Titel | The Human brain is best described as being on a female/male continuum: Evidence from a neuroimaging connectivity study |
| Autor(in); Institution |
Zhang, Yi; Shanghai Centre for Mathematical Sciences, Fudan University, Shanghai, CHINA
Luo, Qiang; Institute of Science and Technology for Brain-Inspired Intelligence, Ministry of Education-Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence and Research and Research Institute of Intelligent Complex Systems, Fudan University, Shanghai, CHINA
Huang, Chu-Chung; Institute of Science and Technology for Brain-Inspired Intelligence, Ministry of Education-Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence and Research and Research Institute of Intelligent Complex Systems, Fudan University, Shanghai, CHINA
Lo, Chun-Yi Zac; Institute of Science and Technology for Brain-Inspired Intelligence, Ministry of Education-Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence and Research and Research Institute of Intelligent Complex Systems, Fudan University, Shanghai, CHINA
Langley, Christelle; Department of Psychiatry, University of Cambridge, Cambridge, UK
Desriviers, Sylvane; Medical Research Council-Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King’s College London, London, UK
Quinlan, Erin Burke; Medical Research Council-Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King’s College London, London, UK
Banaschewski, Tobias; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GERMANY
Millenet, Sabina; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GERMANY
Bokde, Arun L. W.; Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, IRELAND
Flor, Herta; Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Manheim,GERMANY
Garavan, Hugh; Departments of Psychiatry and Psychology, University of Vermont, Burlington, USA
Gowland, Penny; Sir Peter Mansfield Imaging Centre School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK
Heinz, Andreas; Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité, Universitätsmedizin Berlin, Berlin, GERMANY
Ittermann, Bernd; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Martinot, Jean-Luc; Institut National de la Santé et de la Recherche Médicale (INSERM) Unit 1000, Neuroimaging and Psychiatry, University Paris Sud–Paris Saclay, University Paris Descartes, Paris, FRANCE
Artiges, Eric; Institut National de la Santé et de la Recherche Médicale (INSERM) Unit 1000, Neuroimaging and Psychiatry, University Paris Sud–Paris Saclay, University Paris Descartes, Paris, FRANCE
Paillere-Martinot, Marie-Laure; Institut National de la Santé et de la Recherche Médicale (INSERM) Unit 1000, Neuroimaging and Psychiatry, University Paris Sud–Paris Saclay, University Paris Descartes, Paris, FRANCE
Nees, Frauke; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GERMANY
Papadopoulos Orfanos, Dimitri; Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, GERMANY
Poustka, Luise; Clinic for Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, AUSTRIA
Fröhner, Juliane H.; School of Psychology and Global Brain Health Institute, Trinity College Dublin, Dublin, IRELAND
Smolka, Michael N.; Department of Psychiatry and Neuroimaging Center, Technische Universität Dresden, Dresden, GERMANY
Walter, Henrik; Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité, Universitätsmedizin Berlin, Berlin, GERMANY
Whelan, Robert; School of Psychology and Global Brain Health Institute, Trinity College Dublin, Dublin, IRELAND
Tsai, Shih-Jen; Department of Psychiatry, Taipei Veterans General Hospital, Taipei, TAIWAN
Lin, Ching-Po; Institute of Science and Technology for Brain-Inspired Intelligence, Ministry of Education-Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence and Research and Research Institute of Intelligent Complex Systems, Fudan University, Shanghai, CHINA
Bullmore, Ed; Department of Psychiatry, University of Cambridge, Cambridge, UK
Schumann, Gunter; PONS Research Group, Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Berlin, GERMANY
Sahakian, Barbara J.; Institute of Science and Technology for Brain-Inspired Intelligence, Ministry of Education-Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence and Research and Research Institute of Intelligent Complex Systems, Fudan University, Shanghai, CHINA
Feng, Jianfeng; Shanghai Centre for Mathematical Sciences, Fudan University, Shanghai, CHINA
|
| Quelle/Jahr | Cerebral Cortex: 31 (2021), 6, 3021 - 3033 |
| ISSN | 1047-3211 (PRINT) ; 1460-2199 (ONLINE) |
| DOI | |
| Verlag | Oxford: Oxford Univ. Pr. |
| Freie Schlagworte | androgyny ; brain functional network ; sex difference |
| Zusammenfassung | Psychological androgyny has long been associated with greater cognitive f lexibility, adaptive behavior, and better mental health, but whether a similar concept can be defined using neural features remains unknown. Using the neuroimaging data from 9620 participants, we found that global functional connectivity was stronger in the male brain before middle age but became weaker after that, when compared with the female brain, after systematic testing of potentially confounding effects. We defined a brain gender continuum by estimating the likelihood of an observed functional connectivity matrix to represent a male brain. We found that participants mapped at the center of this continuum had fewer internalizing symptoms compared with those at the 2 extreme ends. These findings suggest a novel hypothesis proposing that there exists a neuroimaging concept of androgyny using the brain gender continuum, which may be associated with better mental health in a similar way to psychological androgyny. |
| Kostenfreier Zugang | Open Access Hybrid |
| Rechteinformation | CC BY 4.0 ; Creative Commons Attribution 4.0 License |
| Themenbereich der Metrologie | Metrologie in der Medizin |
Zitierung
Zhang, Y., Luo, Q., Huang, C.-C., Lo, C.-Y. Z., Langley, C., Desriviers, S., Quinlan, E. B., Banaschewski, T., Millenet, S., Bokde, A. L. W., Flor, H., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.-L., Artiges, E., Paillere-Martinot, M.-L., Nees, F., Papadopoulos Orfanos, D., Poustka, L., Fröhner, J. H., Smolka, M. N., Walter, H., Whelan, R., Tsai, S.-J., Lin, C.-P., Bullmore, E., Schumann, G., Sahakian, B. J., & Feng, J. (2021). The Human brain is best described as being on a female/male continuum: Evidence from a neuroimaging connectivity study. Cerebral Cortex, 31(6), 3021–3033. https://doi.org/10.1093/cercor/bhaa408