Zugriffsnummer 45333
Dokumenttyp Zeitschriftenartikel Open Access Hybrid
Peer Review mit Peer Review
Sprache Englisch
Titel 3D Free-breathing multichannel absolute B+1 mapping in the human body at 7T
Autor(in); Institution
Dietrich, Sebastian; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Aigner, Christoph Stefan; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Kolbitsch, Christoph; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Mayer, Johannes; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Ludwig, Juliane; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Schmidt, Simon; Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, GERMANY
Schäffter, Tobias; 8, Medizinphysik und metrologische Informationstechnik, PTB-Berlin
Schmitter, Sebastian; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Quelle/Jahr Magnetic Resonance in Medicine: 85 (2021), 5, 2552 - 2567
ISSN 0740-3194 (PRINT) ; 1522-2594 (ONLINE)
DOI
Verlag London: Wiley
Freie Schlagworte 7 Tesla ; actual flip angle imaging ; body imaging ; B+1 mapping ; radial phase encoding ; ultrahigh field
Zusammenfassung Purpose: To introduce and investigate a method for free-breathing three-dimensional (3D) B+1 mapping of the human body at ultrahigh field (UHF), which can be used to generate homogenous flip angle (FA) distributions in the human body at UHF. Methods: A 3D relative B+1 mapping sequence with a radial phase-encoding (RPE) k-space trajectory was developed and applied in 11 healthy subjects at 7T. An RPEbased actual flip angle mapping method was applied with a dedicated B+1 shim setting to calibrate the relative B+1 maps yielding absolute B+1 maps of the individual transmit channels. The method was evaluated in a motion phantom and by multidimensional in vivo measurements. Additionally, 3D gradient echo scans with and without static phase-only B+1 shims were used to qualitatively validate B+1 shim predictions. Results: The phantom validation revealed good agreement for B+1 maps between dynamicmeasurement and static reference acquisition. The proposed 3D method was successfully validated in vivo by comparing magnitude and phase distributions with a 2D Cartesian reference. 3D B+1 maps free from visible motion artifacts were successfully acquired for 11 subjects with body mass indexes ranging from 19 kg/m2  to 34 kg/m2 . 3D respirationresolved absolute B+1 maps indicated FA differences between inhalation and exhalation up to 15% for one channel and up to 24% for combined channels for shallow breathing. Conclusion: The proposed method provides respiration-resolved absolute 3D B+1 maps of the human body at UHF, which enables the investigation and development of 3D B+1shimming and parallel transmission methods to further enhance body imaging at UHF.
Kostenfreier Zugang Open Access Hybrid
Rechteinformation CC BY 4.0 ; Creative Commons Attribution 4.0 License
Themenbereich der Metrologie Metrologie in der Medizin
Förderinformationen (1) Förderername: Deutsche Forschungsgemeinschaft (DFG)
Förderer ID: 0000 0001 2096 9829
Förderer ID Typ: ISNI
Förderprogramm: Grant/Award Nr SCHM 2677/2-1 ; GRK2260 BIOQIC

Zitierung

Dietrich, S., Aigner, C. S., Kolbitsch, C., Mayer, J., Ludwig, J., Schmidt, S., Schäffter, T., & Schmitter, S. (2021). 3D Free-breathing multichannel absolute B⁺₁ mapping in the human body at 7T. Magnetic Resonance in Medicine, 85(5), 2552–2567. https://doi.org/10.1002/mrm.28602

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