| Zugriffsnummer | 44670 |
| Dokumenttyp | Konferenzartikel |
| Peer Review | unbekannt |
| Sprache | Englisch |
| Titel | Temperature triggered release of a protein from thermoresponsive nanogels using thermal magnetic resonance |
| Autor(in); Institution |
Ji, Y.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, GERMANY
Winter, Lukas; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Navarro, L.; Institute of Chemistry and Biochemistry, Freie Universität Berlin, Berlin, GERMANY
Ku, M.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, GERMANY
Periquito, J.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, GERMANY
Pham, M.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, GERMANY
Hoffmann, Werner; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Theune, L.; Institute of Chemistry and Biochemistry, Freie Universität Berlin, Berlin, GERMANY
Calderon, M.; Institute of Chemistry and Biochemistry, Freie Universität Berlin, Berlin, GERMANY
Niendorf, T.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, GERMANY
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| Quelle/Jahr | Proceedings of the 2020 ISMRM & SMRT Virtual Conference & Exhibition ; IN: Proceedings of the International Society for Magnetic Resonance in Medicine: 28 (2020), 4 S. |
| Artikelnummer | 1129 |
| Availability | [online only] |
| URL | |
| Verlag | Berkeley, Calif.: ISMRM |
| Konferenzangaben | ISMRM & SMRT Virtual Conference & Exhibition, Virtual Conference, 08-14, August, 2020 |
| Freie Schlagworte | Magnetic resonance imaging ; drug delivery ; thermal magnetic resonance ; RF induced heating |
| Zusammenfassung | Thermal Magnetic Resonance (ThermalMR) adds a thermal dimension to an MR device by exploiting the constructive interference of radiofrequency (RF) waves for temperature intervention. Here, the capacity of ThermalMR is demonstrated in a model system involving the release of a protein from thermoresponsive nanogels. Upon RF heating the nanogels (T=43°C), 29.3% of the protein were released after 6h which is in accordance with the release profile obtained for the reference data derived from a water bath setup. ThermalMR provides an ideal testbed for the study of temperature induced release of drugs, MR probes and other agents from thermoresponsive carriers. [Conference did take place as virtual conference because of Covid-19 virus pandemic] |
| Themenbereich der Metrologie | Metrologie in der Medizin |
Zitierung
Ji, Y., Winter, L., Navarro, L., Ku, M., Periquito, J., Pham, M., Hoffmann, W., Theune, L., Calderon, M., & Niendorf, T. (2020). Temperature triggered release of a protein from thermoresponsive nanogels using thermal magnetic resonance. ISMRM & SMRT Virtual Conference & Exhibition, Virtual Conference, 08-14, August, 2020.