| Zugriffsnummer | 44192 |
| Dokumenttyp | Zeitschriftenartikel |
| Peer Review | mit Peer Review |
| Sprache | Englisch |
| Titel | Sampling and mass detection of a countable number of microparticles using on-cantilever imprinting |
| Autor(in); Institution |
Nyang‘au, Wilson Ombati; Technische Universität Braunschweig, Institute of Semiconductor Technology (IHT) and Laboratory for Emerging Nanometrology (LENA), Braunschweig, GERMANY; Department of Metrology, Kenya Bureau of Standards (KEBS), Nairobi, KENYA
Setiono, Andi; Technische Universität Braunschweig, Institute of Semiconductor Technology (IHT) and Laboratory for Emerging Nanometrology (LENA), Braunschweig, GERMANY; Research Center for Physics, Indonesian Institute of Sciences (LIPI), Kawasan Puspiptek Serpong, Tangerang Selatan, INDONESIA
Schmidt, Angelika; Technische Universität Braunschweig, Institute of Semiconductor Technology (IHT) and Laboratory for Emerging Nanometrology (LENA), Braunschweig, GERMANY
Bosse, Harald; 5, Fertigungsmesstechnik, PTB-Braunschweig
Peiner, Erwin; Technische Universität Braunschweig, Institute of Semiconductor Technology (IHT) and Laboratory for Emerging Nanometrology (LENA), Braunschweig, GERMANY
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| Quelle/Jahr | Sensors: 20 (2020), 9, 1 - 20 |
| Artikelnummer | 2508 |
| Availability | [online only] |
| ISSN | 1424-8220 |
| DOI | |
| Verlag | Basel: MDPI |
| Freie Schlagworte | piezoresistive microcantilever mass sensor ; resonant frequency ; dispensing tip ; droplet ; particle sampling ; adsorption ; PMMA ; magnetic polystyrene particles |
| Zusammenfassung | Liquid-borne particles sampling and cantilever-based mass detection are widely applied in many industrial and scientific fields e.g., in the detection of physical, chemical, and biological particles, and disease diagnostics, etc. Microscopic analysis of particles-adsorbed cantilever-samples can provide a good basis for measurement comparison. However, when a particles-laden droplet on a solid surface is vaporized, a cluster-ring deposit is often yielded which makes particles counting difficult or impractical. Nevertheless, in this study, we present an approach, i.e., oncantilever particles imprinting, which effectively defies such odds to sample and deposit countable single particles on a sensing surface. Initially, we designed and fabricated a triangular microcantilever sensor whose mass m0, total beam-length L, and clamped-end beam-width w are equivalent to that of a rectangular/normal cantilever but with a higher resonant frequency (271 kHz), enhanced sensitivity (0.13 Hz/pg), and quality factor (˜3000). To imprint particles on these cantilever sensors, various calibrated stainless steel dispensing tips were utilized to pioneer this study by dipping and retracting each tip from a small particle-laden droplet (resting on a hydrophobic n-type silicon substrate), followed by tip-sensor-contact (at a target point on the sensing area) to detach the solution (from the tip) and adsorb the particles, and ultimately determine the particles mass concentration. Upon imprinting/adsorbing the particles on the sensor, resonant frequency response measurements were made to determine the mass (or number of particles). A minimum detectable mass of ˜0.05 pg was demonstrated. To further validate and compare such results, cantilever samples (containing adsorbed particles) were imaged by scanning electron microscopy (SEM) to determine the number of particles through counting (from which, the lowest count of about 11 magnetic polystyrene particles was obtained). The practicality of particle counting was essentially due to monolayer particle arrangement on the sensing surface. Moreover, in this work, the main measurement process influences are also explicitly examined. |
| Kostenfreier Zugang | Open Access Gold |
| Rechteinformation | CC BY 4.0 ; Creative Commons Attribution 4.0 License |
| Themenbereich der Metrologie | Nanometrologie |
| Forschungsprojekt | 17IND05: MicroProbes: Multifunctional ultrafast microprobes for on-the-machine measurements |
| Förderinformationen (1) |
Förderername: European Commission (EC)
Förderer ID: 0000 0001 2242 8989 Förderer ID Typ: ISNI Förderprogramm: EMPIR 2017 Industry Titel der Förderung: 17IND05: MicroProbes: Multifunctional ultrafast microprobes for on-the-machine measurements Förderungsnummer: 17IND05 |