| Zugriffsnummer | 43115 |
| Dokumenttyp | Zeitschriftenartikel |
| Peer Review | mit Peer Review |
| Sprache | Englisch |
| Titel | European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND) |
| Autor(in); Institution |
Düzel, E.; Institute of Cognitive Neurology and Dementia Research, Otto-von-Guericke University Magdeburg, Magdeburg, GERMANY; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, GERMANY; Institute of Cognitive Neuroscience, University College London, London, UK
Acosta-Cabronero, J.; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Magdeburg, GERMANY; Wellcome Centre for Human Neuroimaging, UCL Queen Square Institute of Neurology, University College London, London, UK
Berron, D.; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Magdeburg, GERMANY; University BioImaging Center, Lund University, Lund, SWEDEN
Biessels, G.; Department of Neurology, UMC Utrecht, Utrecht University, Utrecht, THE NETHERLANDS
Björkman-Burtscher, I.; Departement of Radiology, Sahlgrenska Akademy, University of Gothenburg, Gothenburg, SWEDEN
Bottlaender, M.; NeuroSpin, CEA & Université Paris-Saclay, Gif-Sur-Yvette, FRANCE
Bowtell, R.; Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK
von Buchem, M; Department of Radiology, University Medical Center Leiden, Leiden, THE NETHERLANDS
Cardenas-Blanco, A.; Institute of Cognitive Neurology and Dementia Research, Otto-von-Guericke University Magdeburg, Magdeburg, GERMANY
Boumezbeur, F.; NeuroSpin, CEA & Université Paris-Saclay, Gif-Sur-Yvette, FRANCE
Chan, D.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
Clare, S.; Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, UK
Costagli, M.; Laboratory of Medical Physics and Magnetic Resonance, IRCCS Stella Maris, Pisa, ITALY
de Rochefort, L.; Center for Magnetic Resonance in Biology and Medicine, CRMBM, CNRS - Aix Marseille Université, Marseille, FRANCE
Fillmer, Ariane; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Gowland, P.; Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK
Hansson, O.; Lund University BioImaging Center, Lund University, Lund, SWEDEN
Hendrikse, J.; Department of Neurology, UMC Utrecht, Utrecht University, Utrecht, THE NETHERLANDS
Kraff, O.; Erwin L. Hahn Institute for Magnetic Resonance Imaging, University of Duisburg-Essen, Essen, GERMANY
Ladd, M.E.; Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, GERMANY
Ronen, I.; Department of Radiology, University Medical Center Leiden, Leiden, THE NETHERLANDS
Petersen, E.; Danish Center for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, DENMARK
Rowe, J. B.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
Siebner, H.; Danish Center for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, DENMARK
Stoecker, T.; German Center for Neurodegenerative Diseases (DZNE), Bonn, GERMANY
Straub, S.; Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, GERMANY
Tosetti, M.; Imago 7 Research Foundation, Pisa, ITALY
Uludag, K.; Center for Neuroscience Imaging Research, Institute for Basic Science and Department of Biomedical Engineering, Sungkyunkwan University, Suwon, REPUBLIC OF KOREA
Vignaud, A.; NeuroSpin, CEA & Universite Paris-Saclay, Gif-Sur-Yvette, FRANCE
Zwanenburg, J.; Department of Neurology, UMC Utrecht, Utrecht University, Utrecht, THE NETHERLANDS
Speck, O.; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Magdeburg, GERMANY; Center for Behavioral Brain Science, Magdeburg, GERMANY
|
| Quelle/Jahr | Alzheimer's and Dementia: 11 (2019), 538 - 549 |
| ISSN | 1552-5260 (PRINT) ; 1552-5279 (ONLINE) |
| DOI | |
| Verlag | Amsterdam [u.a.]: Elsevier |
| Freie Schlagworte | Magnetic resonance imaging (MRI) ; Ultrahigh-field MRI ; Alzheimer’s disease (AD) ; Subjective cognitive decline(SCD) ; Mild cognitive impairment (MCI) ; Parkinson’s disease (PD) ; Vascular dementia |
| Zusammenfassung | Introduction: The goal of European Ultrahigh-Field Imaging Network in Neurodegenerative Diseases (EUFIND) is to identify opportunities and challenges of 7 Tesla (7T) MRI for clinical andresearch applications in neurodegeneration. EUFIND comprises 22 European and one US site, including over 50 MRI and dementia experts as well as neuroscientists. Methods: EUFIND combined consensus workshops and data sharing for multisite analysis, focusingon 7 core topics: clinical applications/clinical research, highest resolution anatomy, functional imaging, vascular systems/vascular pathology, iron mapping and neuropathology detection, spectroscopy,and quality assurance. Across these topics, EUFIND considered standard operating procedures,safety, and multivendor harmonization. Results: The clinical and research opportunities and challenges of 7T MRI in each subtopic are setout as a roadmap. Specific MRI sequences for each subtopic were implemented in a pilot study presented in this report. Results show that a large multisite 7T imaging network with highly advancedand harmonized imaging sequences is feasible and may enable future multicentre ultrahigh-fieldMRI studies and clinical trials. Discussion: The EUFIND network can be a major driver for advancing clinical neuroimagingresearch using 7T and for identifying use-cases for clinical applications in neurodegeneration. |
| Kostenfreier Zugang | Open Access Hybrid |
| Rechteinformation | CC BY-NC-ND 4.0 ; Creative Commons Attribution NonCommercial NoDerivatives 4.0 License |
| Themenbereich der Metrologie | Metrologie in der Medizin |
Zitierung
Düzel, E., Acosta-Cabronero, J., Berron, D., Biessels, G., Björkman-Burtscher, I., Bottlaender, M., Bowtell, R., von Buchem, M., Cardenas-Blanco, A., Boumezbeur, F., Chan, D., Clare, S., Costagli, M., de Rochefort, L., Fillmer, A., Gowland, P., Hansson, O., Hendrikse, J., Kraff, O., Ladd, M., Ronen, I., Petersen, E., Rowe, J. B., Siebner, H., Stoecker, T., Straub, S., Tosetti, M., Uludag, K., Vignaud, A., Zwanenburg, J., & Speck, O. (2019). European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND). Alzheimer's and Dementia, 11, 538–549. https://doi.org/10.1016/j.dadm.2019.04.010