Nanodosimetry - on the "tracks" of biological radiation effectiveness

Rabus, Hans

doi:https://doi.org/10.1016/j.zemedi.2020.01.002

Zugriffsnummer	43032
Dokumenttyp	Zeitschriftenartikel
Peer Review	mit Peer Review
Sprache	Englisch
Titel	Nanodosimetry - on the "tracks" of biological radiation effectiveness
Autor(in); Institution	Rabus, Hans; 6.5, Strahlenwirkung, PTB-Braunschweig
Quelle/Jahr	Zeitschrift für Medizinische Physik: 30 (2019), 2, 91 - 94
ISSN	0939-3889
DOI	https://doi.org/10.1016/j.zemedi.2020.01.002
URL	https://arxiv.org/abs/1903.06408 https://arxiv.org/abs/1903.06408v1
Verlag	Amsterdam: Elsevier
Freie Schlagworte	Nanodosimetry ; track structure ; radiation quality ; radiobiological effectiveness
Zusammenfassung	Biological effectiveness of a certain absorbed dose of ionizing radiation depends on the radiation quality, i. e. the spectrum of ionizing particles and their energy distribution. As has been shown in several studies, the biological effectiveness is related to the pattern of energy deposits on the microscopic scale, the so-called track structure. Clusters of lesions in the DNA molecule within site sizes of few nanometers play a particular role in this context. This work presents a brief overview of nanodosimetric approaches to relate biological effects with track structure derived quantities and experimental techniques to derive such quantities.

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Rabus, H. (2019). Nanodosimetry - on the "tracks" of biological radiation effectiveness. Zeitschrift für Medizinische Physik, 30(2), 91–94. https://doi.org/10.1016/j.zemedi.2020.01.002

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