| Zugriffsnummer | 40950 |
| Dokumenttyp | Zeitschriftenartikel |
| Peer Review | mit Peer Review |
| Sprache | Englisch |
| Titel | Multiband diffusion-weighted MRI of the eye and orbit free of geometric distortions using a RARE-EPI hybrid |
| Autor(in); Institution |
Paul, K.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, GERMANY
Huelnhagen, T.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, GERMANY
Oberacker, E.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, GERMANY
Wenz, D.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, GERMANY
Schubert, Florian; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Kühne, A.; MRI.TOOLS GmbH, Berlin, GERMANY
Waiczies, H.; MRI.TOOLS GmbH, Berlin, GERMANY; MRI.TOOLS GmbH, Berlin, GERMANY
Schmitter, Sebastian; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Stachs, O.; Department of Ophthalmology, University of Rostock, Rostock, GERMANY
Niendorf, T.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, GERMANY; Experimental and Clinical Research Center (ECRC), a joint cooperation between the Charité Medical Faculty and the Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, GERMANY
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| Quelle/Jahr | NMR in Biomedicine: 31 (2018), 3, 1 - 18 |
| Artikelnummer | e3872 |
| Availability | [online only] |
| ISSN | 1099-1492 |
| DOI | |
| Verlag | New York, NY: Wiley |
| Freie Schlagworte | applications ; methods and engineering ; diffusion weighted imaging ; diffusion methods ; diffusion MR sequences ; methods and engineering ; human study ; neruological |
| Zusammenfassung | Diffusion-weighted imaging (DWI) provides information on tissue microstructure. Single-shot echo planar imaging (EPI) is the most common technique for DWI applications in the brain, but is prone to geometric distortions and signal voids. Rapid acquisition with relaxation enhancement [RARE, also known as fast spin echo (FSE)] imaging presents a valuable alternative to DWI with high anatomical accuracy. This work proposes a multi-shot diffusion-weighted RARE-EPI hybrid pulse sequence, combining the anatomical integrity of RARE with the imaging speed and radiofrequency (RF) power deposition advantage of EPI. The anatomical integrity of RARE-EPI was demonstrated and quantified by center of gravity analysis for both morphological images and diffusion-weighted acquisitions in phantom and in vivo experiments at 3.0 T and 7.0 T. The results indicate that half of the RARE echoes in the echo train can be replaced by EPI echoes whilst maintaining anatomical accuracy. The reduced RF power deposition of RARE-EPI enabled multiband RF pulses facilitating simultaneous multi-slice imaging. This study shows that diffusion-weighted RARE-EPI has the capability to acquire high fidelity, distortion-free images of the eye and the orbit. It is shown that RARE-EPI maintains the immunity to B0 inhomogeneities reported for RARE imaging. This benefit can be exploited for the assessment of ocular masses and pathological changes of the eye and the orbit. |
Zitierung
Paul, K., Huelnhagen, T., Oberacker, E., Wenz, D., Schubert, F., Kühne, A., Waiczies, H., Schmitter, S., Stachs, O., & Niendorf, T. (2018). Multiband diffusion-weighted MRI of the eye and orbit free of geometric distortions using a RARE-EPI hybrid. NMR in Biomedicine, 31(3), 1–18. https://doi.org/10.1002/nbm.3872