Zugriffsnummer 40290
Dokumenttyp Zeitschriftenartikel
Peer Review mit Peer Review
Sprache Englisch
Titel Extending the construct network of trait disinhibition to the neuroimaging domain: Validation of a bridging scale for use in the European IMAGEN Project
Autor(in); Institution
Brislin, S. J.; Florida State University, Tallahassee, FL, USA
Patrick, C. J.; Florida State University, Tallahassee, FL, USA
Flor, H.; Heidelberg University, Mannheim, GERMANY
Nees, F.; Heidelberg University, Mannheim, GERMANY
Heinrich, A.; Heidelberg University, Mannheim, GERMANY
Drislane, L. E.; University of Michigan, Ann Arbor, MI, USA
Yancey, J. R.; Florida State University, Tallahassee, FL, USA
Banaschewski, T.; Heidelberg University, Mannheim, GERMANY
Bokde, A. L. W.; The University of Dublin, Dublin, IRELAND
Bromberg, U.; University Medical Centre Hamburg-Eppendorf, Hamburg, GERMANY
Büchel, C.; University Medical Centre Hamburg-Eppendorf, Hamburg, GERMANY
Quinlan, E. B.; King's College London, London, England, UK
Desrivières, S.; King's College London, London, England, UK
Frouin, V.; Université Paris-Saclay, Gif-sur-Yvette, FRANCE
Garavan, H.; University of Vermont, Burlington, VT, USA
Gowland, P.; University of Nottingham, University Park, Nottingham, UK
Heinz, A.; Charité-Universitätsmedizin Berlin, Berlin, GERMANY
Ittermann, Bernd; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin
Martinot, J. L.; University Paris Sud, Orsay, FRANCE; University Paris Descartes, Paris, France; Université Paris-Sorbonne, Paris, FRANCE
Martinot, M. P.; Maison de Solenn, Cochin Hospital, Paris, FRANCE
Papadopoulos Orfanos, D.; Université Paris-Saclay, Gif-sur-Yvette, FRANCE
Poustka, L.; Heidelberg University, Mannheim, GERMANY; Medical University of Vienna, Vienna, AUSTRIA
Fröhner, J. H.; Technische Universität Dresden, Dresden, GERMANY
Smolka, M. N.; Technische Universität Dresden, Dresden, GERMANY
Walter, H.; Charité-Universitätsmedizin Berlin, Berlin, GERMANY
Whelan, R.; University College Dublin, Dublin, IRELAND
Conrod, P.; Université de Montréal, Quebec, CANADA
Stringaris, A.; National Institute of Mental Health, Bethesda, MD, USA
Struve, M.; Heidelberg University, Mannheim, GERMANY
van Noort, B.; Charité-Universitätsmedizin Berlin, Berlin, GERMANY
Grimmer, Y.; Heidelberg University, Mannheim, GERMANY
Fadai, T.; University Medical Centre Hamburg-Eppendorf, Hamburg, GERMANY
Schumann, G.; King's College London, London, England, UK
Foell, J.; Florida State University, Tallahassee, FL, USA
Quelle/Jahr Assessment: 26 (2019), 4, 567 - 581
ISSN 1073-1911 (PRINT) ; 1552-3489 (ONLINE)
DOI
Verlag Thousand Oaks, Calif: Sage Publications
Freie Schlagworte externalizing psychopathology ; trait disinhibition ; liability ; neuroimaging ; IMAGEN
Zusammenfassung Trait disinhibition, a clinical-liability construct, has well-established correlates in the diagnostic, self-rating, task-behavioral, and brain potential response domains. Recently, studies have begun to test for neuroimaging correlates of this liability factor, but more work of this type using larger data sets is needed to clarify its brain bases. The current study details the development and validation of a scale measure of trait disinhibition composed of questionnaire items available in the IMAGEN project, a large-scale longitudinal study of factors contributing to substance abuse that includes clinical interview, self-report personality, task-behavioral, neuroimaging, and genomic measures. Using a construct-rating and psychometric refinement approach, a scale was developed that evidenced: (a) positive relations with interview-assessed psychopathology in the IMAGEN sample, both concurrently and prospectively and (b) positive associations with scale measures of disinhibition and reported psychopathology, and a robust negative correlation with P3 brain response, in a separate adult sample (Mage = 19.5). These findings demonstrate that a common scale measure can index this construct from adolescence through to early adulthood, and set the stage for systematic work directed at identifying neural and genetic biomarkers of this key liability construct using existing and future data from the IMAGEN project.

Zitierung

Brislin, S. J., Patrick, C. J., Flor, H., Nees, F., Heinrich, A., Drislane, L. E., Yancey, J. R., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Quinlan, E. B., Desrivières, S., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J. L., Martinot, M. P., Papadopoulos Orfanos, D., Poustka, L., Fröhner, J. H., Smolka, M. N., Walter, H., Whelan, R., Conrod, P., Stringaris, A., Struve, M., van Noort, B., Grimmer, Y., Fadai, T., Schumann, G., & Foell, J. (2019). Extending the construct network of trait disinhibition to the neuroimaging domain: Validation of a bridging scale for use in the European IMAGEN Project. Assessment, 26(4), 567–581. https://doi.org/10.1177/1073191118759748

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