| Zugriffsnummer | 40273 |
| Dokumenttyp | Zeitschriftenartikel |
| Peer Review | mit Peer Review |
| Sprache | Englisch |
| Titel | High-resolution whole-brain diffusion MRI at 7T using radiofrequency parallel transmission |
| Autor(in); Institution |
Wu, X.; Radiology, Medical School, University of Minnesota, Minneapolis, MN, USA
Auerbach, E. J.; Radiology, Medical School, University of Minnesota, Minneapolis, MN, USA
Vu, A. T.; Center for Imaging of Neurodegenrative Diseases, VA Healthcare System, San Francisco, CA, USA
Moeller, S.; Radiology, Medical School, University of Minnesota, Minneapolis, MN, USA
Lenglet, C.; Radiology, Medical School, University of Minnesota, Minneapolis, MN, USA
Schmitter, Sebastian; 8.1, Biomedizinische Magnetresonanz, PTB-Berlin; Radiology, Medical School, University of Minnesota, Minneapolis, MN, USA
Van de Moortele, P.-F.; Radiology, Medical School, University of Minnesota, Minneapolis, MN, USA
Yacoub, E.; Radiology, Medical School, University of Minnesota, Minneapolis, MN, USA
Ugurbil, K.; Radiology, Medical School, University of Minnesota, Minneapolis, MN, USA
|
| Quelle/Jahr | Magnetic Resonance in Medicine: 80 (2018), 5, 1857 - 1870 |
| ISSN | 0740-3194 (PRINT) ; 1522-2594 (ONLINE) |
| DOI | |
| Verlag | Wiley |
| Freie Schlagworte | parallel transmission ; diffusion MRI ; high-field MRI ; human connectome project |
| Zusammenfassung | Purpose Investigating the utility of RF parallel transmission (pTx) for Human Connectome Project (HCP)‐style whole‐brain diffusion MRI (dMRI) data at 7 Tesla (7T). Methods Healthy subjects were scanned in pTx and single‐transmit (1Tx) modes. Multiband (MB), single‐spoke pTx pulses were designed to image sagittal slices. HCP‐style dMRI data (i.e., 1.05‐mm resolutions, MB2, b‐values = 1000/2000 s/mm2, 286 images and 40‐min scan) and data with higher accelerations (MB3 and MB4) were acquired with pTx. Results pTx significantly improved flip‐angle detected signal uniformity across the brain, yielding ∼19% increase in temporal SNR (tSNR) averaged over the brain relative to 1Tx. This allowed significantly enhanced estimation of multiple fiber orientations (with ∼21% decrease in dispersion) in HCP‐style 7T dMRI datasets. Additionally, pTx pulses achieved substantially lower power deposition, permitting higher accelerations, enabling collection of the same data in 2/3 and 1/2 the scan time or of more data in the same scan time. Conclusion pTx provides a solution to two major limitations for slice‐accelerated high‐resolution whole‐brain dMRI at 7T; it improves flip‐angle uniformity, and enables higher slice acceleration relative to current state‐of‐the‐art. As such, pTx provides significant advantages for rapid acquisition of high‐quality, high‐resolution truly whole‐brain dMRI data. . |
Zitierung
Wu, X., Auerbach, E. J., Vu, A. T., Moeller, S., Lenglet, C., Schmitter, S., Van de Moortele, P.-F., Yacoub, E., & Ugurbil, K. (2018). High-resolution whole-brain diffusion MRI at 7T using radiofrequency parallel transmission. Magnetic Resonance in Medicine, 80(5), 1857–1870. https://doi.org/10.1002/mrm.27189