| Zugriffsnummer | 39560 |
| Dokumenttyp | Konferenzartikel |
| Peer Review | unbekannt |
| Sprache | Englisch |
| Titel | Long-term stable measurement phantoms for quantitative magnetic particle imaging |
| Autor(in); Institution |
Wöckel, L.; Institute of Biomedical Engineering and Informatics (BMTI), Technische Universität Ilmenau, Ilmenau, GERMANY
Behr, V.C.; Department of Experimental Physics 5 (Biophysics), University of Würzburg, Würzburg, GERMANY
Grüttner, C.; micromod Partikeltechnologie GmbH, Rostock, GERMANY
Kosch, Olaf; 8.2, Biosignale, PTB-Berlin
Mattern, A.; Institute of Biomedical Engineering and Informatics (BMTI), Technische Universität Ilmenau, Ilmenau, GERMANY
Vogel, P.; Department of Experimental Physics 5 (Biophysics), University of Würzburg, Würzburg, GERMANY; Department of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, GERMANY
Wells, James; 8.2, Biosignale, PTB-Berlin
Wiekhorst, Frank; 8.2, Biosignale, PTB-Berlin
Dutz, S.; Institute of Biomedical Engineering and Informatics (BMTI), Technische Universität Ilmenau, Ilmenau, GERMANY
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| Quelle/Jahr | 16th German Ferrofluid Workshop: Dresden July 17th – 19th 2017:(2017), 120 - 121 |
| Konferenzangaben | 16th Ferrofluid Workshop 2017, Dresden, 17-19, July, 2017, GERMANY |
| Zusammenfassung | Since the first description of the MPI principle in 2005, a variety of laboratory MPI scanners have been reported at locations all over the world. In 2014 the first commercial scanners were brought onto the market by Bruker Biospin. These scanners enable the reconstruction of the spatial distribution of magnetic nanoparticles (MNP) within tissue, which is of major importance for many applications of MNP in biomedicine. To enable researchers to explore the potential of this promising novel imaging modality, the detection limits and image resolutions of the present MPI scanners have to be assessed as major performance determining parameters. For this, well-defined and comparable magnetic structures are needed to perform comparison studies between the MPI setups of different laboratores. Up to now, each laboratory uses its own measurement phantoms. Mostly, these phantoms consist of MNP at a certain concentration filled into containers of different volume. Such phantoms often exhibit no longterm stability, and thus do not allow ring test studies between different labs and scanners. In this study, we developed dedicated phantoms to monitor and assess relevant imaging properties of an MPI scanner. In particular, the spatial resolution, the capability for MNP quantification of and furthermore, the long-term behavior of the used MNP-matrix combinations are addressed. |
