| Zugriffsnummer | 39556 |
| Dokumenttyp | Konferenzartikel |
| Peer Review | unbekannt |
| Sprache | Englisch |
| Titel | Multifunctional nanoclusters for theranostics in cancer |
| Autor(in); Institution |
Lyer, S.; Universitätsklinikum Erlangen, Department of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius Stiftung-Professorship, Erlangen, GERMANY
Knopp, T.; Universitätsklinikum Hamburg-Eppendorf, Diagnostic and Interventional Radiology Department and Clinic, Hamburg-Eppendorf, GERMANY
Werner, F.; Universitätsklinikum Hamburg-Eppendorf, Diagnostic and Interventional Radiology Department and Clinic, Hamburg-Eppendorf, GERMANY
Zaloga, J.; Universitätsklinikum Erlangen, Department of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius Stiftung-Professorship, Erlangen, GERMANY
Friedrich, R.; Universitätsklinikum Erlangen, Department of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius Stiftung-Professorship, Erlangen, GERMANY
Trahms, Lutz; 8.2, Biosignale, PTB-Berlin
Wiekhorst, Frank; 8.2, Biosignale, PTB-Berlin
Struffert, T.; Universitätsklinikum Erlangen, Department of Radiology/Neuroradiology, Erlangen, GERMANY
Engelhorn, T.; Universitätsklinikum Erlangen, Department of Radiology/Neuroradiology, Erlangen, GERMANY
Dörfler, A.; Universitätsklinikum Erlangen, Department of Radiology/Neuroradiology, Erlangen, GERMANY
Bäuerle, T.; Universitätsklinikum Erlangen, Department of Radiology/Neuroradiology, Erlangen, GERMANY
Uder, M.; Universitätsklinikum Erlangen, Department of Radiology/Neuroradiology, Erlangen, GERMANY
Tietze, R.; Universitätsklinikum Erlangen, Department of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius Stiftung-Professorship, Erlangen, GERMANY
Janko, C.; Universitätsklinikum Erlangen, Department of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius Stiftung-Professorship, Erlangen, GERMANY
Alexiou, C.; Universitätsklinikum Erlangen, Department of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius Stiftung-Professorship, Erlangen, GERMANY
Dutz, S.; Institut für Biomedizinische Technik und Informatik, Technische Universität Ilmenau, Ilmenau, GERMANY
Hochhaus, A.; Klinik für Innere Medizin II, Abt. Hämatologie & Internistische Onkologie, Universitätsklinikum Jena, Jena, GERMANY
Clement, J.H.; Klinik für Innere Medizin II, Abt. Hämatologie & Internistische Onkologie, Universitätsklinikum Jena, Jena, GERMANY
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| Quelle/Jahr | 16th German Ferrofluid Workshop: Dresden July 17th – 19th 2017:(2017), 106 - 107 |
| Konferenzangaben | 16th Ferrofluid Workshop 2017, Dresden, 17-19, July, 2017, GERMANY |
| Zusammenfassung | Aim of the Section of Experimental Oncology and Nanomedicine (SEON) is to utilize PIONs for the treatment of cancerand arteriosclerosis by MDT. Therefore,over a period of several years we developed SPIONs optimized for the purpose of magnetic drug delivery. These particles show a very good biocompatibility, are very stable in human and animal blood and can carry a sufficient drug load. Due to their magnetic properties, these particles can be accumulated in a target area by magnetic fields and first results show they can be heated with alternating magnetic fields. These SPIONs were also suitable for MRI-imaging but from the theoretical point of view not optimal for Magnetic Particle Imaging (MPI), because they are clusters of a size between 60 nm and 70 nm with a single core diameter of approximately 7,6 nm. The aim of this study was to show, that multifunctional nanoclusters, which are suitable for magnetic drug targeting, hyperthermia, MR-imaging can also show a signal in MPI. |
Zitierung
Lyer, S., Knopp, T., Werner, F., Zaloga, J., Friedrich, R., Trahms, L., Wiekhorst, F., Struffert, T., Engelhorn, T., Dörfler, A., Bäuerle, T., Uder, M., Tietze, R., Janko, C., Alexiou, C., Dutz, S., Hochhaus, A., & Clement, J. (2017). Multifunctional nanoclusters for theranostics in cancer. 16th Ferrofluid Workshop 2017, Dresden, 17-19, July, 2017, GERMANY.