| Zugriffsnummer | 39554 |
| Dokumenttyp | Konferenzartikel |
| Sprache | Englisch |
| Titel | Comparing the spectra of magnetic nanoparticles measured by magnetic particle imaging and magnetic particle spectroscopy |
| Autor(in); Institution |
Paysen, Hendrik; 8.2, Biosignale, PTB-Berlin
Wells, James; 8.2, Biosignale, PTB-Berlin
Kosch, Olaf; 8.2, Biosignale, PTB-Berlin
Löwa, Norbert; 8.2, Biosignale, PTB-Berlin
Steinhoff, Uwe; 8.2, Biosignale, PTB-Berlin
Trahms, Lutz; 8.2, Biosignale, PTB-Berlin
Schäffter, Tobias; 8, Medizinphysik und metrologische Informationstechnik, PTB-Berlin
Wiekhorst, Frank; 8.2, Biosignale, PTB-Berlin
|
| Quelle/Jahr | 16th German Ferrofluid Workshop: Dresden July 17th – 19th 2017:(2017), 56 - 57 |
| Konferenzangaben | 16th Ferrofluid Workshop 2017, Dresden, 17-19, July, 2017, GERMANY |
| Zusammenfassung | Quantitative Imaging of magnetic nanoparticles (MNP) has great potential for biomedical applications. Magnetic Particle Imaging (MPI) is a new technology capable of safe, fast and spatially resolved quantification of MNP distributions in vivo. The technique utilizes spectral analysis of the non-linear dynamic magnetic response of MNP exposed to a harmonic excitation field. Combined with static gradient fields for spatial encoding and a calibration measurement, the measured spectra are used to reconstruct a quantitative map of the iron amount. However, the quantitative information contained in MPI data is not yet fully understood. Here, we present results acquired with an adapted MPI scanner to work as a conventional magnetic particle spectrometer (MPS). For this purpose only one excitation coil is used at a single frequency without signal generation at mixed frequencies. This way the raw measurement data can be directly compared to a calibrated MPS device, where the quantitative information is already well known. The performance of both systems is compared and the detection limits are presented. |
Zitierung
Paysen, H., Wells, J., Kosch, O., Löwa, N., Steinhoff, U., Trahms, L., Schäffter, T., & Wiekhorst, F. (2017). Comparing the spectra of magnetic nanoparticles measured by magnetic particle imaging and magnetic particle spectroscopy. 16th Ferrofluid Workshop 2017, Dresden, 17-19, July, 2017, GERMANY.