Zugriffsnummer 39385
Dokumenttyp Zeitschriftenartikel Open Access Hybrid
Peer Review mit Peer Review
Sprache Englisch
Titel Determination of cavitation probabilities and cavitation thresholds using a single focusing transducer to induce and detect cavitation events: I. Method and terminology
Autor(in); Institution
Haller, Julian; 1.6, Schall, PTB-Braunschweig
Wilkens, Volker; 1.6, Schall, PTB-Braunschweig
Shaw, Adam; National Physical Laboratory (NPL), Acoustics and Ionizing Radiation Division, Teddington, UK
Quelle/Jahr Ultrasound in Medicine and Biology: 44 (2018), 2, 377 - 396
ISSN 0301-5629 (PRINT) ; 1879-291X (ONLINE)
DOI
Verlag Amsterdam [u.a.]: Elsevier
Klassifikationscode PACS: 43.25.Yw ; PACS: 43.80.+p ; PACS: 43.34.Wa
Freie Schlagworte Acoustic cavitation threshold ; Agar Phantom ; High-intensity focused ultrasound
Zusammenfassung In this paper a method to determine cavitation probabilities in tissue-mimicking materials (TMMs) is described that uses a high-intensity focused ultrasound (HIFU) transducer both for inducing and detecting the cavitation events. The method has been evaluated by studying cavitation probabilities in Agar-based TMMs with and without scatterers and for different sonication modes like continuous wave, single pulses (microseconds to milliseconds) and burst signals. Cavitation thresholds (defined here as the peak rarefactional in situ pressure at which the cavitation probability reaches 50 %) at a frequency of 1.06 MHz were observed between 1.1 MPa (for 1 s continuous wave sonication) and 4.6 MPa (for 1 s burst signal with 25 cycles burst length and 10 ms burst period) in a 3 % (by weight) Agar phantom without scatterers. This paper describes the method and its evaluation as well as giving general terminology useful for standardizing the description of insonation conditions and comparing results. In an accompanying second paper, the presented method is used to systematically study the cavitation thresholds in the same material for a range of sonication modes.
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Rechteinformation CC BY-NC-ND 4.0 ; Creative Commons Attribution NonCommercial NoDerivatives 4.0 License

Zitierung

Haller, J., Wilkens, V., & Shaw, A. (2018). Determination of cavitation probabilities and cavitation thresholds using a single focusing transducer to induce and detect cavitation events: I. Method and terminology. Ultrasound in Medicine and Biology, 44(2), 377–396. https://doi.org/10.1016/j.ultrasmedbio.2017.08.1946

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