| Zugriffsnummer | 37997 |
| Dokumenttyp | Konferenzartikel in Zeitschrift |
| Peer Review | unbekannt |
| Sprache | Englisch |
| Titel | Preparing system functions for quantitative MPI |
| Autor(in); Institution |
Kosch, Olaf; 8.2, Biosignale, PTB-Berlin
Heinen, U.; Department of Electrical Engineering & Information Technology, University of Applied Sciences, Pforzheim, GERMANY
Wells, James; 8.2, Biosignale, PTB-Berlin
Trahms, Lutz; 8.2, Biosignale, PTB-Berlin
Wiekhorst, Frank; 8.2, Biosignale, PTB-Berlin
|
| Quelle/Jahr | International Journal on Magnetic Particle Imaging: 3 (2017), 2, 1 - 7 |
| Artikelnummer | 706002 |
| ISSN | 2365-9033 |
| DOI | |
| Verlag | Lübeck: Infinite Sc. Publishing |
| Konferenzangaben | 7th International Workshop on Magnetic Particle Imaging (IWMPI2017) , Prague, Czech Republic, Prague, 23-24, March, 2017, Czech Republic |
| Freie Schlagworte | quantitative MPI ; system function analysis ; concentration influence |
| Zusammenfassung | Magnetic particle imaging (MPI) pledges to provide quantitative information on the spatial distribution of magnetic nanoparticle (MNP). Using a figure-of-eight shaped hosepipe phantom filled with the MPI Tracer Ferucarbotran (Resovist precursor), we investigated the quantification capability of a commercial preclinical MPI-scanner (Bruker/Philips Preclinical MPI System, Germany) operated at Charité university hospital, Berlin. For reconstruction of the measured MNP distribution, we used a set of four system functions (SF) acquired with a tracer reference at different iron concentrations (in the range 0.1 mol/L to 1 mol/L). From the analysis of a selected region of interest in the reconstructed images, we found a linear relation between voxel values and the inverse of the concentration of the corresponding reference used in the particular SF acquisition. Based on the precisely known total tracer quantity, we analyzed the MPI image to find the amount of tracer present in each voxel of the phantom. This result was found to be independent of the concentration of the reference sample used in the SF acquisition. |
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| Rechteinformation | CC BY 4.0 ; Creative Commons Attribution 4.0 License ; Original article under Creative Commons Attribution 4.0 International License |