| Zugriffsnummer | 36085 |
| Dokumenttyp | Zeitschriftenartikel |
| Peer Review | unbekannt |
| Sprache | Englisch |
| Titel | Prediction of alcohol drinking in adolescents: Personality-traits, behavior, brain responses, and genetic variations in the context of reward sensitivity |
| Autor(in); Institution |
Heinrich, A.; Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GERMANY
Müller, K.U.; Neuroimaging Center, Department of Psychiatry and Psychotherapy, Technische Universität Dresden, GERMANY
Banaschewski, T.; Department of Child and Adolescent Psychiatry and Psychotherapy, Clinical Faculty Mannheim, Central Institute of Mental Health, University of Heidelberg, Mannheim, GERMANY
Barker, G.J.; Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK
Bokde, AL.; Institute of Neuroscience and Discipline of Psychiatry, School of Medicine, Trinity College Dublin, Dublin, IRELAND
Bromberg, U.; Universitätsklinikum Hamburg Eppendorf, Hamburg, GERMANY
Büchel, C.; University Medical Centre Hamburg-Eppendorf, Hamburg, GERMANY
Conrod, P.; Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK
Fauth-Bühler, M.; Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GERMANY
Papadopoulos, D.; Neurospin, Commissariat à l'Energie Atomique et aux Energies Alternatives, Paris, FRANCE
Gallinat, J.; Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, GERMANY
Garavan, H.; Discipline of Psychiatry, School of Medicine, Trinity College Dublin, Dublin, IRELAND
Gowland, P.; School of Physics and Astronomy, University of Nottingham, Nottingham, UK
Heinz, A.; Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité–Universitätsmedizin Berlin, GERMANY
Ittermann, Bernd; 8.1, Medizinische Messtechnik, PTB-Berlin
Mann, K.; Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GERMANY
Martinot, J.L.; Institut National de la Santé et de la Recherche Médicale, INSERM Unit 1000 “Neuroimaging & Psychiatry”, Université Paris Sud, Orsay, and AP-HP Department of Adolescent Psychopathology and Medicine, Maison de Solenn, Université Paris Descartes, Paris, FRANCE
Paus, T.; Rotman Research Institute, University of Toronto, Toronto, ON, CANADA; School of Psychology, University of Nottingham, Nottingham, UK
Pausova, Z.; The Hospital for Sick Children, University of Toronto, Toronto, ON, CANADA
Smolka, M.; Neuroimaging Center, Department of Psychiatry and Psychotherapy, Technische Universität Dresden, Dresden, GERMANY
Ströhle, A.; Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité-Universitätsmedizin Berlin, GERMANY
Rietschel, M.; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GERMANY
Flor, H.; Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GERMANY
Schumann, G.; Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK
Nees, F.; Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, GERMANY
|
| Quelle/Jahr | Biological Psychology: 118 (2016), 79 - 87 |
| ISSN | 0301-0511 (PRINT) ; 1873-6246 (ONLINE) |
| DOI | |
| Verlag | Amsterdam [u.a.]: Elsevier |
| Freie Schlagworte | Prediction of alcohol consumption ; Adolescents ; Longitudinal study ; Personality ; Behavior ; Brain responses ; Genetic variations |
| Zusammenfassung | Adolescence is a time that can set the course of alcohol abuse later in life. Sensitivity to reward on multiple levels is a major factor in this development. We examined 736 adolescents from the IMAGEN longitudinal study for alcohol drinking during early (mean age=14.37) and again later (mean age=16.45) adolescence. Conducting structural equation modeling we evaluated the contribution of reward-related personality traits, behavior, brain responses and candidate genes. Personality seems to be most important in explaining alcohol drinking in early adolescence. However, genetic variations in ANKK1 (rs1800497) and HOMER1 (rs7713917) play an equal role in predicting alcohol drinking two years later and are most important in predicting the increase in alcohol consumption. We hypothesize that the initiation of alcohol use may be driven more strongly by personality while the transition to increased alcohol use is more genetically influenced. |
Zitierung
Heinrich, A., Müller, K., Banaschewski, T., Barker, G., Bokde, A., Bromberg, U., Büchel, C., Conrod, P., Fauth-Bühler, M., Papadopoulos, D., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Mann, K., Martinot, J., Paus, T., Pausova, Z., Smolka, M., Ströhle, A., Rietschel, M., Flor, H., Schumann, G., & Nees, F. (2016). Prediction of alcohol drinking in adolescents: Personality-traits, behavior, brain responses, and genetic variations in the context of reward sensitivity. Biological Psychology, 118, 79–87. https://doi.org/10.1016/j.biopsycho.2016.05.002