Zugriffsnummer 35637
Dokumenttyp Zeitschriftenartikel
Peer Review unbekannt
Sprache Englisch
Titel Ion induced fragmentation cross-sections of DNA constituents
Autor(in); Institution
Rudek, Benedikt; 6.6, Strahlenwirkung, PTB-Braunschweig
Arndt, Alexander; 6.6, Strahlenwirkung, PTB-Braunschweig
Bennett, Daniel; 6.6, Strahlenwirkung, PTB-Braunschweig
Wang, Mingjie; 6.6, Strahlenwirkung, PTB-Braunschweig
Rabus, Hans; 6.6, Strahlenwirkung, PTB-Braunschweig
Quelle/Jahr The European Physical Journal D: 69 (2015), 237, 1 - 9
ISSN 1434-6079 (PRINT) ; 1434-6079 (ONLINE)
DOI
URL
Verlag Berlin: Springer
Freie Schlagworte DNA ; impact ionization ; fragmentation ; cross-sections
Zusammenfassung Proton collision with chemical analogs for the base, the sugar and the phosphor residue of the DNA, namely pyrimidine, tetrahydrofuran and trimethyl phosphate, respectively, has been investigated. The impact energies ranged from 300 keV up to 16 MeV. For the first time, relative fragmentation cross sections for proton impact are reported for tetrahydrofuran and trimethyl phosphate; previously reported cross sections for pyrimidine are extended for energies beyond 2500 keV. Ionization of tetrahydrofuran leads to a ring break in about 80% of all events, trimethyl phosphate predominantly fragments by bond cleavage to one of the three methyl-groups and for pyrimidine the parent ion has the highest abundance. Such comparison supports earlier findings that the sugar is the weak spot for strand breaks.

Zitierung

Rudek, B., Arndt, A., Bennett, D., Wang, M., & Rabus, H. (2015). Ion induced fragmentation cross-sections of DNA constituents. The European Physical Journal D, 69(237), 1–9. https://doi.org/10.1140/epjd/e2015-60204-7

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