| Zugriffsnummer | 34064 |
| Dokumenttyp | Konferenzartikel |
| Peer Review | unbekannt |
| Sprache | Englisch |
| Titel | Eight channel Tx/Rx RF coil array for 1H/19F MR of the human knee and fluorinated drugs at 7.0 T |
| Autor(in); Institution |
Ji, Y.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, GERMANY
Waiczies, H.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, GERMANY; MRI.TOOLS GmbH, Berlin, GERMANY
Winter, L.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, GERMANY; MRI.TOOLS GmbH, Berlin, GERMANY
Neumanova, P.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, GERMANY
Hofmann, D.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, GERMANY
Rieger, J.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, GERMANY; MRI.TOOLS GmbH, Berlin, GERMANY
Mekle, Ralf; 8.1, Medizinische Messtechnik, PTB-Berlin
Waiczies, S.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, GERMANY
Niendorf, Th.; Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, GERMANY; Experimental and Clinical Research Center (ECRC), a joint cooperation between the Charité Medical Faculty and the Max-Delbrueck Center, Berlin, GERMANY
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| Quelle/Jahr | ISMRM 23th Annual Meeting & Exhibition: 30 May - 5 June, 2015; Toronto, Canada:(2015), 1 S. |
| Availability | [CD-ROM] ; file name: 1934.pdf |
| ISSN | 1545-4428 |
| Verlag | Berkeley, Calif.: ISMRM |
| Konferenzangaben | 23th ISMRM Annual Meeting & Exhibition, Toronto, 30 May – 5 June, 2015, Canada |
| Freie Schlagworte | 7T ; Eight channel RF coil ; Human Knee ; Fluorinated Drugs |
| Zusammenfassung | The virtual absence of fluorine (19F) in biological tissues encourages the use of 19F MR for in vivo tracking and quantification of fluorine containing exogenous agents. However, the sensitivity limit for 19F detection constitutes an impediment for translational research and clinical applications of in vivo 19F MR, illustrated by the limited number of reports referring to 19F MR in humans. Realizing these limitations and the intrinsic sensitivity gain at higher magnetic field strengths, it is appealing to pursue in vivo 19F MR at UHF strengths (B0 ≥ 7.0 T). This work proposes a modular, double-tuned 1H/19F eight channel Tx/Rx RF coil array tailored for knee imaging to examine the feasibility of human 1H/19F MR at 7.0 T. The suitability of the proposed approach for 19F MR, following topical application of an ointment containing flufenamic acid (FA), a 19F-containing non-steroidal anti-inflammatory drug, is demonstrated. |
Zitierung
Ji, Y., Waiczies, H., Winter, L., Neumanova, P., Hofmann, D., Rieger, J., Mekle, R., Waiczies, S., & Niendorf, T. (2015). Eight channel Tx/Rx RF coil array for ¹H/¹⁹F MR of the human knee and fluorinated drugs at 7.0 T. 23th ISMRM Annual Meeting & Exhibition, Toronto, 30 May – 5 June, 2015, Canada.