| Zugriffsnummer | 31239 |
| Dokumenttyp | Zeitschriftenartikel |
| Peer Review | mit Peer Review |
| Sprache | Englisch |
| Titel | Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink |
| Autor(in); Institution |
Spinelli, L.; Consiglio Nazionale delle Ricerche–Istituto di Fotonica e Nanotecnologie, Milano, ITALY
Botwicz, M.; Nalecz Instutute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, POLAND
Zolek, N.; Nalecz Instutute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, POLAND
Kacprzak, M.; Nalecz Instutute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, POLAND
Milej, D.; Nalecz Instutute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, POLAND
Sawosz, P.; Nalecz Instutute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, POLAND
Liebert, A.; Nalecz Instutute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, POLAND
Weigel, U.; Institut de Ciencies Fotoniques, Parc Mediterrani de la Tecnologia, Castelldefels, SPAIN
Durduran, T.; Institut de Ciencies Fotoniques, Parc Mediterrani de la Tecnologia, Castelldefels, SPAIN
Foschum, F.; Institut für Lasertechnologien in der Medizin und Messtechnik an der Universität Ulm, GERMANY
Kienle, A.; Institut für Lasertechnologien in der Medizin und Messtechnik an der Universität Ulm, GERMANY
Baribeau, F.; National Optics Institute, Québec, CANADA
Leclair, S.; National Optics Institute, Québec, CANADA
Bouchard, J.-P.; National Optics Institute, Québec, CANADA
Noiseux, I.; National Optics Institute, Québec, CANADA
Gallant, P.; National Optics Institute, Québec, CANADA
Mermut, O.; National Optics Institute, Québec, CANADA
Farina, A.; Consiglio Nazionale delle Ricerche–Istituto di Fotonica e Nanotecnologie, Milano, ITALY
Pifferi, A.; Consiglio Nazionale delle Ricerche–Istituto di Fotonica e Nanotecnologie, Milano, ITALY
Torricelli, A.; Politecnico di Milano–Dipartimento di Fisica, Milano, ITALY
Cubeddu, R.; Consiglio Nazionale delle Ricerche–Istituto di Fotonica e Nanotecnologie, Milano, ITALY
Ho, H.-C.; Industrial Technology Research Institute, Hsinchu, TAIWAN
Mazurenka, Mikhail; 8.3, Biomedizinische Optik, PTB-Berlin
Wabnitz, Heidrun; 8.3, Biomedizinische Optik, PTB-Berlin
Klauenberg, Katy; 8.4, Mathematische Modellierung und Datenanalyse, PTB-Berlin
Bodnar, Olha; 8.4, Mathematische Modellierung und Datenanalyse, PTB-Berlin
Elster, Clemens; 8.4, Mathematische Modellierung und Datenanalyse, PTB-Berlin
Bénazech-Lavoué, M.; Département de génie électrique, Université de Sherbrooke, CANADA
Bérubé-Lauzière, Y.; Département de génie électrique, Université de Sherbrooke, CANADA
Lesage, F.; Département de génie électrique, École Polytechnique de Montreal, CANADA
Khoptyar, D.; Department of Physics, Lund University, SWEDEN
Subash, A. A.; Department of Physics, Lund University, SWEDEN
Andersson-Engels, S.; Department of Physics, Lund University, SWEDEN
Di Ninni, P.; Dipartimento di Fisica e Astronomia, Universita degli Studi di Firenze, ITALY
Martelli, F.; Dipartimento di Fisica e Astronomia, Universita degli Studi di Firenze, ITALY
Zaccanti, G.; Dipartimento di Fisica e Astronomia, Universita degli Studi di Firenze, ITALY
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| Quelle/Jahr | Biomedical Optics Express: 5 (2014), 7, 2037 - 2053 |
| Availability | [online only] |
| ISSN | 2156-7085 (ONLINE) |
| DOI | |
| Verlag | Washington, DC: Optical Society of America |
| Klassifikationscode | OCIS: 170.5280 ; OCIS: 170.7050 ; OCIS: 170.3890 |
| Freie Schlagworte | Photon migration ; Turbid media ; Medical optics instrumentation |
| Zusammenfassung | A multi-center study has been set up to accurately characterize the optical properties of diffusive liquid phantoms based on Intralipid and India ink at near-infrared (NIR) wavelengths. Nine research laboratories from six countries adopting different measurement techniques, instrumental set-ups, and data analysis methods determined at their best the optical properties and relative uncertainties of diffusive dilutions prepared with common samples of the two compounds. By exploiting a suitable statistical model, comprehensive reference values at three NIR wavelengths for the intrinsic absorption coefficient of India ink and the intrinsic reduced scattering coefficient of Intralipid-20% were determined with an uncertainty of about 2% or better, depending on the wavelength considered, and 1%, respectively. Even if in this study we focused on particular batches of India ink and Intralipid, the reference values determined here represent a solid and useful starting point for preparing diffusive liquid phantoms with accurately defined optical properties. Furthermore, due to the ready availability, low cost, long-term stability and batch-to-batch reproducibility of these compounds, they provide a unique fundamental tool for the calibration and performance assessment of diffuse optical spectroscopy instrumentation intended to be used in laboratory or clinical environment. Finally, the collaborative work presented here demonstrates that the accuracy level attained in this work for optical properties of diffusive phantoms is reliable. |
| Kostenfreier Zugang | Open Access Gold |
Zitierung
Spinelli, L., Botwicz, M., Zolek, N., Kacprzak, M., Milej, D., Sawosz, P., Liebert, A., Weigel, U., Durduran, T., Foschum, F., Kienle, A., Baribeau, F., Leclair, S., Bouchard, J.-P., Noiseux, I., Gallant, P., Mermut, O., Farina, A., Pifferi, A., Torricelli, A., Cubeddu, R., Ho, H.-C., Mazurenka, M., Wabnitz, H., Klauenberg, K., Bodnar, O., Elster, C., Bénazech-Lavoué, M., Bérubé-Lauzière, Y., Lesage, F., Khoptyar, D., Subash, A. A., Andersson-Engels, S., Di Ninni, P., Martelli, F., & Zaccanti, G. (2014). Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink. Biomedical Optics Express, 5(7), 2037–2053. https://doi.org/10.1364/boe.5.002037