| Zugriffsnummer | 30709 |
| Dokumenttyp | Konferenzartikel in Zeitschrift |
| Sprache | Englisch |
| Titel | Quantitative reconstruction of a magnetic nanoparticle distribution using a non-negativity constraint |
| Autor(in); Institution |
Liebl, Maik; 8.2, Biosignale, PTB-Berlin
Steinhoff, Uwe; 8.2, Biosignale, PTB-Berlin
Wiekhorst, Frank; 8.2, Biosignale, PTB-Berlin
Coene, A.; Department of Electrical Energy, Systems and Automation, Ghent University,Ghent, BELGIUM
Haueisen, J.; Institute of Biomedical Engineering and Informatics, Ilmenau University of Technology, Ilmenau, GERMANY
Trahms, Lutz; 8.2, Biosignale, PTB-Berlin
|
| Quelle/Jahr | Proceedings BMT 2013, DGBMT Jahrestagung, 3-Länder-Tagung D-A-CH, Austria, Graz. Biomedizinische Technik: 58 (2013), Suppl. 1, 2 S. |
| ISSN | 0013-5585 (PRINT) ; 1862-278X (ONLINE) |
| DOI | |
| Verlag | Berlin ; Boston: de Gruyter |
| Konferenzangaben | BMT 2013, DGBMT Jahrestagung, 3-Länder-Tagung D-A-CH, Austria, Graz, Graz, 19-21, September, 2013, Germany |
| Freie Schlagworte | Magnetorelaxometry ; magnetic nanoparticles ; inhomogeneous magnetizing fields ; spatial encoding |
| Zusammenfassung | Magnetorelaxometry (MRX) is a non-invasive method for the specific quantification of magnetic nanoparticles (MNP). Here, we investigate experimentally the reconstruction of the MNP concentration in an extended volume. A phantom with varying but known MNP distribution was subsequently magnetized by 48 planar coils at different locations. The MRX signal was measured using the PTB 304 SQUID-magnetometer system. The inverse problem was solved by means of a non-negative least squares (NNLS) algorithm and compared to a minimum norm estimation (TSVD-MNE). The reconstruction by NNLS shows a deviation of the total MNP amount of less than 3% (10% by TSVD-MNE). Hence, adapted non-invasive MRX methods can reliable reconstruct the MNP content in extended volumes. |
Zitierung
Liebl, M., Steinhoff, U., Wiekhorst, F., Coene, A., Haueisen, J., & Trahms, L. (2013). Quantitative reconstruction of a magnetic nanoparticle distribution using a non-negativity constraint. Biomedizinische Technik, 58(Suppl. 1), 2 S. https://doi.org/10.1515/bmt-2013-4261