| Zugriffsnummer | 25985 |
| Dokumenttyp | Zeitschriftenartikel |
| Peer Review | unbekannt |
| Sprache | Englisch |
| Titel | Dose uncertainty in radiotherapy of patients with head and neck cancer measured by in vivo ESR/alanine dosimetry using a mouthpiece |
| Autor(in); Institution |
Wagner, Daniela; University Hospital Göttingen, Department of Radiotherapy and Radiooncology, Göttingen, GERMANY
Anton, Mathias; 6.2, Dosimetrie für Strahlentherapie und Röntgendiagnostik, PTB-Braunschweig
Vorwerk, Hilke; University Hospital Göttingen, Department of Radiotherapy and Radiooncology, Göttingen, GERMANY
|
| Quelle/Jahr | Physics in Medicine and Biology: 56 (2011), 5, 1373 - 1383 |
| ISSN | 0031-9155 |
| DOI | |
| URL | |
| Verlag | Bristol: IOP Publishing |
| Klassifikationscode | PACS: 87.53.Bn ; PACS: 87.19.X ; PACS: 87.50.sj ; PACS: 87.55.-x ; PACS: 87.53.Kn ; PACS: 87.59.bd |
| Freie Schlagworte | radiation therapy ; alanine ; electron spin resonance ; in vivo ; dosimetry ; head and neck cancer |
| Zusammenfassung | During IMRT radiotherapy of patients with head and neck cancer, the doses accumulated next to the mucosa were measured in five patients and compared to the dose calculated by the treatment planning system. The comparison of the applied and measured dose for each measurement point showed in six of the eight alanine probe positions a good agreement within the given relative combined standard uncertainty of less than 4.5% for an accumulated dose of 30 Gy and less than 4.6% for an accumulated dose of 8 Gy, respectively. The dominant contribution to the overall uncertainty for the in vivo measurements was the positioning of the probes in the patient’s body and their corresponding localization in the CT data as well as the incaccuracy of the available algorithm for dose distribution calculation at the low-density material / soft tissue interface between the mouthpiece and the mucosa. |
Zitierung
Wagner, D., Anton, M., & Vorwerk, H. (2011). Dose uncertainty in radiotherapy of patients with head and neck cancer measured by in vivo ESR/alanine dosimetry using a mouthpiece. Physics in Medicine and Biology, 56(5), 1373–1383. https://doi.org/10.1088/0031-9155/56/5/010