Zugriffsnummer 20737
Dokumenttyp Konferenzartikel
Sprache Englisch
Titel Fluorescence imaging of experimental rheumatoid arthritis in vivo using a fast flying-spot scanner
Autor(in); Institution
Berger, Jörn; 8.3, Biomedizinische Optik, PTB-Berlin
Voigt, Jan; 8.3, Biomedizinische Optik, PTB-Berlin
Seifert, Frank; 8.1, Medizinische Messtechnik, PTB-Berlin
Ebert, Bernd; 8.3, Biomedizinische Optik, PTB-Berlin
Macdonald, Rainer; 8.3, Biomedizinische Optik, PTB-Berlin
Gemeinhardt, I.; Department of Radiology, Charité – Universitätsmedizin Berlin, GERMANY
Gemeinhardt, O.; Faculty of Veterinary Medicine, Institute of Veterinary Anatomy, Freie Universität Berlin, GERMANY
Schnorr, J.; Department of Radiology, Charité – Universitätsmedizin Berlin, GERMANY
Taupitz, M.; Department of Radiology, Charité – Universitätsmedizin Berlin, GERMANY
Vater, A.; Bayer Schering Pharma AG, Research Laboratories, Berlin, GERMANY
Vollmer, S.; Bayer Schering Pharma AG, Research Laboratories, Berlin, GERMANY
Licha, K.; Bayer Schering Pharma AG, Research Laboratories, Berlin, GERMANY
Schirner, M.; Bayer Schering Pharma AG, Research Laboratories, Berlin, GERMANY
Quelle/Jahr Novel optical instrumentation for biomedical applications III: 17 - 19 June 2007, Munich, Germany:(2007), 66310U3 - 66310U6
Schriftenreihe Proceedings of SPIE: 6631 ; Progress in biomedical optics and imaging: 8,44
Herausgeber(in)
Depeursinge, Christian D.
ISSN 1605-7422
ISBN 978-0-8194-6775-1
DOI
Verlag Bellingham, Wash.: SPIE
Konferenzangaben European Conference on Biomedical Optics, München, 17-21, June, 2007, Germany
Zusammenfassung We have developed a flying-spot scanner for fluorescence imaging of rheumatoid arthritis in the near infrared (NIR) spectral range following intravenous administration of contrast agents. The new imaging system has been characterized with respect to linearity, dynamic range and spatial resolution with the help of fluorescent phantoms. In vivo experiments were performed on an animal model of rheumatoid arthritis. Finally, NIR-fluorescence images of early stages of joint inflammation have been compared with findings from contrast enhanced MR imaging and histology.

Zitierung

Berger, J., Voigt, J., Seifert, F., Ebert, B., Macdonald, R., Gemeinhardt, I., Gemeinhardt, O., Schnorr, J., Taupitz, M., Vater, A., Vollmer, S., Licha, K., & Schirner, M. (2007). Fluorescence imaging of experimental rheumatoid arthritis in vivo using a fast flying-spot scanner. European Conference on Biomedical Optics, München, 17-21, June, 2007, Germany. https://doi.org/10.1117/12.728307

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