| Zugriffsnummer | 20180 |
| Dokumenttyp | Konferenzartikel in Zeitschrift |
| Peer Review | unbekannt |
| Sprache | Englisch |
| Titel | In vitro investigation of the behaviour of magnetic particles by a circulating artery model |
| Autor(in); Institution |
Seliger, Christian; Friedrich-Alexander-University, Head and Neck Surgery, Erlangen, GERMANY
Jurgons, Roland; Friedrich-Alexander-University, Head and Neck Surgery, Erlangen, GERMANY
Wiekhorst, Frank; 8.2, Biosignale, PTB-Berlin
Eberbeck, Dietmar; 8.2, Biosignale, PTB-Berlin
Trahms, Lutz; 8.2, Biosignale, PTB-Berlin
Iro, H.; Friedrich-Alexander-University, Head and Neck Surgery, Erlangen, GERMANY
Alexiou, Christoph; Friedrich-Alexander-University, Head and Neck Surgery, Erlangen, GERMANY
|
| Quelle/Jahr | Proceedings of the Sixth International Conference on the Scientific and Clinical Applications of Magnetic Carriers - SCAMC-06. Journal of Magnetism and Magnetic Materials: 311 (2007), 358 - 362 |
| ISSN | 0304-8853 (PRINT) |
| DOI | |
| Verlag | Amsterdam: Elsevier |
| Konferenzangaben | Sixth International Conference on the Scientific and Clinical Applications of Magnetic Carriers — SCAMC-06, Krems, 17 - 20 May 2006, Austria |
| Freie Schlagworte | Magnetic drug targeting ; Mitoxantrone ; Magnetic nanoparticle ; Chemotherapy ; VX2 tumour |
| Zusammenfassung | Magnetic drug targeting is the use of coated magnetic nanoparticles as carriers for cytostatic drugs. After intraarterial application of these carriers, they are attracted with an external magnetic field to, for example, an experimental VX2 tumour. The biological compatibility of this system depends on several physiological and physical parameters. We established an in vitro model to simulate in vivo conditions in a circulating system consisting of a circuit with an intact bovine femoral artery close to an external magnetic field. Nanoparticle suspensions were applied by a side inlet. After the magnetisation procedure particle size, concentration and distribution was examined |
Zitierung
Seliger, C., Jurgons, R., Wiekhorst, F., Eberbeck, D., Trahms, L., Iro, H., & Alexiou, C. (2007). In vitro investigation of the behaviour of magnetic particles by a circulating artery model. Journal of Magnetism and Magnetic Materials, 311, 358–362. https://doi.org/10.1016/j.jmmm.2006.10.1205