Zugriffsnummer 18884
Dokumenttyp Konferenzartikel
Sprache Englisch
Titel Normal heart beat, alternans and fibrillation in simulations of a model for the rabbit ventricles
Autor(in); Institution
Bauer, Steffen; 8.4, Mathematische Modellierung und Datenanalyse, PTB-Berlin
Röder, G.; TU Berlin, Theoretische Physik, Berlin, GERMANY
Engel, H.; TU Berlin, Theoretische Physik, Berlin, GERMANY
Weber dos Santos, Rodrigo; Universidade Federal de Juiz de Fora, Juiz de Fora, BRAZIL
Koch, Hans; 8, Medizinphysik und metrologische Informationstechnik, PTB-Berlin
Bär, Markus; 8.4, Mathematische Modellierung und Datenanalyse, PTB-Berlin
Quelle/Jahr Cardiovascular oscillations - ESGCO 2006:(2006), 123 - 126
Schriftenreihe Biomedizinische Technik: Special issue
Availability [CD-ROM] ; file name: ESGCO_2006_Proceedings.pdf
Verlag Berlin [u.a.]: de Gruyter
Konferenzangaben Conference and meeting of the European study group on cardiovascular oscillations 2006, Jena, 15-17, May, 2006, Germany
Freie Schlagworte Cardiac propagation ; arrythmias ; modelling
Zusammenfassung Cardiac propagation is investigated by simulations of the modified Beeler-Reuter model using realistic geometry and muscle fibre orientation of the ventricles of a rabbit heart. Electrical excitation is introduced by a periodic pacing of the lower septum of the heart. Depending on the pacing frequency qualitatively different dynamics are observed: namely normal heart beat, T-wave alternans and fibilltion at small, intermediate and large pacing frequencies, respectively. The critical frequency at the onset of alternans and the profiles of the membrane potential agree well with the one obtained in a one-dimensional model and can be explained in terms of the action potential restitution curve.

Zitierung

Bauer, S., Röder, G., Engel, H., Weber dos Santos, R., Koch, H., & Bär, M. (2006). Normal heart beat, alternans and fibrillation in simulations of a model for the rabbit ventricles. Conference and meeting of the European study group on cardiovascular oscillations 2006, Jena, 15-17, May, 2006, Germany.

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