| Zugriffsnummer | 15077 |
| Dokumenttyp | Zeitschriftenartikel |
| Sprache | Englisch |
| Titel | Cyanine dyes as contrast agents in biomedical optical imaging |
| Autor(in); Institution |
Licha, Kai; Schering AG, Research Laboratories, Berlin, GERMANY
Riefke, Björn; Biological Research & Development, Justesa Imagen S.A., Madrid, SPAIN
Ebert, Bernd; 8.12, Biomedizinische Optik und NMR-Messtechnik, PTB-Berlin
Grötzinger, Carsten; Universitätsklinikum Charité der Humboldt Universität zu Berlin, Campus Virchow-Klinikum, Medizinische Klinik m.S. Hepatologie und Gastroenterologie, GERMANY
|
| Quelle/Jahr | Academic Radiology: 9 (2002), 2, Suppl. 1, S320 - S322 |
| ISSN | 1076-6332 (PRINT) ; 1878-4046 (ONLINE) |
| DOI | |
| Verlag | Philadelphia, Pa.: Elsevier |
| Zusammenfassung | Following both the non- specific approach using hydrophilic extracellular derivatives and the receptor-targeted approach using dye-peptide conjugates, the diagnostic potential of cyanine dyes was demonstrated by in vivo animal studies with very small injected doses. We conclude that cyanine dyes are promising contrast agents for the fluorescence-based biomedical optical imaging of tumors and might be of value for many applications which are currently evolving throughout a broad spectrum of clinical disciplines. |
