| Zugriffsnummer | 14572 |
| Dokumenttyp | Zeitschriftenartikel |
| Sprache | Englisch |
| Titel | Non-invasive single-trial monitoring of human movement-related brain activation based on DC-magnetoencephalography |
| Autor(in); Institution |
Mackert, Bruno-Marcel; Neurophysics Group, Dept. of Neurology, Universitätsklinikum Benjamin Franklin, FU Berlin, GERMANY
Wübbeler, Gerd; 8.21, Bioelektrizität und -magnetismus, PTB-Berlin
Leistner, Stefanie; Neurophysics Group, Dept. of Neurology, Universitätsklinikum Benjamin Franklin, FU Berlin, GERMANY
Trahms, Lutz; 8.21, Bioelektrizität und -magnetismus, PTB-Berlin
Curio, Gabriel; Neurophysics Group, Dept. of Neurology, Universitätsklinikum Benjamin Franklin, FU Berlin, GERMANY
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| Quelle/Jahr | NeuroReport: 12 (2001), 8, 1689 - 1692 |
| ISSN | 0959-4965 |
| Verlag | London: Lippincott Williams & Wilkins |
| Freie Schlagworte | Cortical activation ; DC-magnetoencephalography ; Motor-related magnetic fields ; Single trial ; Superconducting quantum interference device |
| Zusammenfassung | Neuroimaging techniques, such as fMRI, PET and near-infrared spectroscopy, monitor task-related neuronal activations in the brain indirectly through the associated neurovascular/metabolic responses. To assess the primary neuronal activations directly, magnetoencephalography was combined here with a mechanical modulation of the head-to-sensor position and signal separation via independent component analysis. In all of five subjects this approach allowed to monitor the time evolution of DC felds ((0.1 Hz) over the left hemisphere related to complex finger movements of the right hand alternating with rest periods (30 s each). Throughout the recording period of 30 min, stable task-related DC fields were recordable in a single-trial mode, i.e. without any averaging. DC-MEG opens up the possibility of analysing non-invasively cortical DC-activity also in stroke, migraine or epilepsy patients. |
