| Zugriffsnummer | 14404 |
| Dokumenttyp | Zeitschriftenartikel |
| Sprache | Englisch |
| Titel | Quantification of optical properties of a breast tumor using random walk theory |
| Autor(in); Institution |
Chernomordik, Victor; National Institutes of Health, National Institute of Child Health and Development, Bethesda, MD, USA
Hattery, David W.; National Institutes of Health, National Institute of Child Health and Development, Bethesda, MD, USA
Grosenick, Dirk; 8.12, Biomedizinische Optik und NMR-Messtechnik, PTB-Berlin
Wabnitz, Heidrun; 8.12, Biomedizinische Optik und NMR-Messtechnik, PTB-Berlin
Rinneberg, Herbert; 8, Medizinphysik und metrologische Informationstechnik, PTB-Berlin
Moesta, K. Thomas; Robert Roessle Hospital, Charité, Humboldt Universität zu Berlin, GERMANY
Schlag, Peter M.; Robert Roessle Hospital, Charité, Humboldt Universität zu Berlin, GERMANY
Gandjbakhche, Amir; National Institutes of Health, National Institute of Child Health and Development, Bethesda, MD, USA
|
| Quelle/Jahr | Journal of Biomedical Optics: 7 (2002), 1, 80 - 87 |
| ISSN | 1083-3668 |
| DOI | |
| Verlag | Bellingham, Wash.: SPIE |
| Freie Schlagworte | Photon migration ; Time-resolved imaging ; Light propagation in tissue ; Differential absorption ; Optical mammography |
| Zusammenfassung | For the first time we use random walk methodology based on time-dependent contrast functions to quantify optical properties of breast tumors (invasive ductal carcinoma) for two patients. Previously this theoretical approach has been successfully applied for analysis of embedded objects in several phantoms. Data analysis was performed on distributions of times of flight for photons transmitted through the breast which have been recorded in vivo using a time-domain scanning mammograph at 670 nm and 785 nm. The size of the tumors, their optical properties and those of the surrounding tissue were reconstructed at both wavelengths. The tumors showed increased absorption and scattering. From the absorption coefficients at both wavelengths blood oxygen saturation was estimated for the tumors and the surrounding tissue. |
Zitierung
Chernomordik, V., Hattery, D. W., Grosenick, D., Wabnitz, H., Rinneberg, H., Moesta, K. T., Schlag, P. M., & Gandjbakhche, A. (2002). Quantification of optical properties of a breast tumor using random walk theory. Journal of Biomedical Optics, 7(1), 80–87. https://doi.org/10.1117/1.1427049