Zugriffsnummer 11017
Dokumenttyp Konferenzartikel
Peer Review unbekannt
Sprache Englisch
Titel Impact of in vivo measured cerebral glutamate on human behavior: the sensation seeking personality trait
Autor(in); Institution
Gallinat, Jürgen; Department of Psychiatry, Charité Universitätsmedizin, Berlin, GERMANY
Bajbouj, Malik; Department of Psychiatry, Charité Universitätsmedizin, Berlin, GERMANY
Schubert, Florian; 8.1, Medizinische Messtechnik, PTB-Berlin
Seifert, Frank; 8.1, Medizinische Messtechnik, PTB-Berlin
Rinneberg, Herbert; 8, Medizinphysik und metrologische Informationstechnik, PTB-Berlin
Quelle/Jahr Magnetic Resonance Materials in Physics, Biology and Medicine : MAGMA ; ESMRMB 2004 : 21st Annual Scientific Meeting: 17 (2004), Suppl.1, 31
Availability [online only]
ISSN 0968-5243 (PRINT) ; 1352-8661 (ONLINE)
DOI
Verlag Berlin: Springer
Konferenzangaben ESMRMB 21th Annual Meeting, Copenhagen, 9-12, September, 2004, Denmark
Zusammenfassung For the first time, significant correlations between absolute cerebral glutamate concentrations (meas-ured by MRS at 3 T) and behavioral traits in humans are reported. Significant negative correlations (controlled for age) between glutamate levels in the ACC and the Sensation Seeking Sum score, as well as the subscales thrill and adventure seeking, and experience seeking were observed. The sub-scales boredom susceptibility or disinhibition did not correlate significantly with glutamate (p)0.05). A significant negative correlation was observed also for the hippocampal glutamate concentration and the SSS. Studies on behavioral effects of cerebral glutamate are important in psychiatric research and may help to develop new agents for psychiatric pharmacotherapy.

Zitierung

Gallinat, J., Bajbouj, M., Schubert, F., Seifert, F., & Rinneberg, H. (2004). Impact of in vivo measured cerebral glutamate on human behavior: the sensation seeking personality trait. ESMRMB 21th Annual Meeting, Copenhagen, 9-12, September, 2004, Denmark. https://doi.org/10.1007/s10334-004-0046-8

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